Klebsiella pneumoniae strain EuSCAPE_EE004

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_EE004 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is characterized by its ability to thrive at an optimal temperature of 37°C and is classified as mesophilic. It possesses flagella, which grants it mobility, and it presents in various arrangements, including chains, pairs, and singles. This strain is predominantly host-associated, with a diverse range of potential hosts, including Homo sapiens (humans), Gallus gallus (chickens), Danio rerio (zebrafish), and various other metazoan and plant species. Notably, Klebsiella pneumoniae is known for its significant pathogenicity in humans, associated with a variety of serious health effects such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain is non-sporulating and has a single replicon and two membranes, which are characteristic features of its cellular structure. Its free-living nature allows it to survive in various environments, contributing to its ecological versatility. In summary, Klebsiella pneumoniae strain EuSCAPE_EE004 exemplifies a highly adaptable pathogen with implications for human health and potential interactions with a wide range of hosts. Its significant pathogenic potential underscores the importance of continued surveillance and research to understand its behavior and impact within both clinical and environmental contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_EE004

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_EE004
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_EE004 genome assembly,

Gene Summary

Adenine Count

1164089 bp

Thymine Count

1165998 bp

Guanine Count

1559965 bp

Cytosine Count

1566540 bp

Genome Length

5456592 bp

Protein-coding Genes

4867 genes

Non-Coding Genes

302 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive88950 - 88961Not Available
Hypothetical proteinSAMEA3499908_00099Not AvailableNegative99672 - 999209175.94
Late control d family proteinSAMEA3499908_00100Not AvailableNegative99966 - 10112042493.1
Trna-met;Not AvailableNot AvailablePositive100691 - 100766Not Available
Tail sheath subtilisin-like domain-containing proteinSAMEA3499908_00101Not AvailablePositive101272 - 10245343051.8
Major tail tube proteinSAMEA3499908_00102Not AvailablePositive102454 - 10296918703.5
Tail proteinSAMEA3499908_00103Not AvailablePositive103021 - 10332010549.7
Tail tape measure proteinSAMEA3499908_00104Not AvailablePositive103483 - 10621896489.9
Tail proteinSAMEA3499908_00105Not AvailablePositive106230 - 10671818190.7
Tail fiber proteinSAMEA3499908_00106Not AvailableNegative106847 - 10791137954.1

Displaying genes 1 – 10 of 5169 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Pyogenic liver abscessCausesPMC12392612
Pyogenic liver abscessesCausesPMC12392612
Liver abscessesCausesPMC12392612
Urinary tract infectionsCausesPMC12915344
PneumoniaCausesPMC12915344
BacteremiaCausesPMC12915344
Liver abscessesCausesPMC12915344
EndophthalmitisCausesPMC12915344
MeningitisCausesPMC12915344
Bloodstream infectionsCausesPMC13168211

Displaying health effects 11 – 20 of 53 in total