Klebsiella pneumoniae strain EuSCAPE_FR022

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_FR022 is a Gram-negative, rod-shaped bacterium categorized as a facultative anaerobe and a chemoheterotroph. This strain typically forms chains, pairs, or exists as single cells and possesses flagella, allowing for mobility. The optimal growth temperature for this strain is 37°C, with a mesophilic temperature range. This bacterium is known to inhabit various hosts, including Homo sapiens (humans), Gallus gallus (chickens), and several other species across Metazoa, Viridiplantae, and Aves. K. pneumoniae strain EuSCAPE_FR022 is associated with numerous health conditions in humans, including severe infections such as bacteremia, urinary tract infections, pneumonia, and sepsis. Its pathogenicity highlights its role as a significant opportunistic pathogen, particularly in individuals with compromised immune systems. The strain is characterized by having one replicon and two membranes, typical of Gram-negative bacteria. As a free-living organism, it demonstrates a diverse ecological niche, allowing it to thrive in various environments, including those associated with human and animal hosts. The extensive range of diseases linked to Klebsiella pneumoniae underscores its importance in public health and the need for ongoing surveillance, particularly in clinical settings where it can lead to serious infections. Understanding its ecological relationships and pathogenic mechanisms can inform strategies for prevention and control of infections caused by this versatile bacterium.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_FR022

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_FR022
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_FR022 genome assembly,

Gene Summary

Adenine Count

1180653 bp

Thymine Count

1186874 bp

Guanine Count

1593803 bp

Cytosine Count

1567958 bp

Genome Length

5529288 bp

Protein-coding Genes

5077 genes

Non-Coding Genes

181 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3500007_00685Not AvailableNegative744089 - 74487728071.5
hxlr family transcriptional regulatorSAMEA3500007_00686Not AvailableNegative744993 - 74544216857.4
glucose-1-phosphataseSAMEA3500007_00687Not AvailablePositive745595 - 74684245605.5
AttlNot AvailableNot AvailablePositive746849 - 746869Not Available
Tyrosine-type recombinase/integraseSAMEA3500007_00688Not AvailableNegative746939 - 74794638274.3
Hypothetical proteinSAMEA3500007_00689Not AvailableNegative748034 - 74833611217.6
Hypothetical proteinSAMEA3500007_00690Not AvailablePositive748432 - 74876412493.2
uncharacterised proteinSAMEA3500007_00691Not AvailablePositive748761 - 7488774058.37
Hypothetical proteinSAMEA3500007_00692Not AvailablePositive748890 - 7491539993.12
Hypothetical proteinSAMEA3500007_00693Not AvailablePositive749165 - 7494048783.41

Displaying genes 1 – 10 of 5258 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
MeningitisCausesPMC13168211
Neonatal sepsisCausesPMC13168211
PneumoniaCausesPMC13253921
Urinary tract infectionsCausesPMC13253921
BacteremiaCausesPMC13253921
Neonatal sepsisCausesPMC13253921
Pyogenic liver abscessCausesPMC13253921
MeningitisCausesPMC13253921
Early onset neonatal sepsisCausesPMC4560869
Pyogenic liver abscessCausesPMC7332619

Displaying health effects 21 – 30 of 53 in total