Klebsiella pneumoniae strain EuSCAPE_FR007

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_FR007 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and chemoheterotroph. This strain is capable of existing in a variety of forms, including chains, pairs, and singles, and exhibits mobility due to the presence of flagella. It thrives optimally at a temperature of 37°C, fitting within the mesophilic temperature range, and possesses a single replicon and two membranes. This strain is known to be associated with various hosts, including Homo sapiens (humans), Gallus gallus (chickens), and a range of other vertebrates and invertebrates such as Danio rerio (zebrafish), Canis lupus familiaris (domestic dogs), and Equidae (horses). Its biotic relationship is classified as free-living, indicating that it can survive independently outside of a host. Klebsiella pneumoniae EuSCAPE_FR007 is notably pathogenic, associated with numerous health effects in humans, such as bacteremia, urinary tract infections, pneumonia, and sepsis. The bacterium is implicated in serious conditions such as liver abscesses, meningitis, and enteritis, highlighting its potential to cause a wide range of infections that can be critical, especially in vulnerable populations. The ecological insight from the data indicates that Klebsiella pneumoniae has a significant role in both environmental and clinical contexts. Its ability to infect multiple host species suggests a versatile adaptability and potential for zoonotic transmission, emphasizing the need for monitoring and understanding its epidemiology in both human and veterinary medicine.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_FR007

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_FR007
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_FR007 genome assembly,

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4949 genes

Non-Coding Genes

195 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dipeptide-binding abc transporter, periplasmic substrate-binding componentSAMEA3499979_00258Not AvailableNegative282215 - 28375656493.9
dipeptide transport atp-binding protein dppdSAMEA3499979_00259Not AvailableNegative283789 - 28564868554.4
l-asparaginaseSAMEA3499979_00260Not AvailableNegative285666 - 28660732679.3
molybdopterin biosynthesis protein moeaSAMEA3499979_00261Not AvailablePositive286843 - 28807844028.0
molybdopterin biosynthesis protein moebSAMEA3499979_00262Not AvailablePositive288078 - 28883327165.9
pyruvate formate-lyase activating enzymeSAMEA3499979_00263Not AvailablePositive288988 - 28988733032.7
pyruvate formate-lyaseSAMEA3499979_00264Not AvailablePositive289892 - 29232490272.6
hydrolaseSAMEA3499979_00265Not AvailablePositive292501 - 29331630111.9
protein of uncharacterised function (duf1479)SAMEA3499979_00266Not AvailablePositive293456 - 29472147307.1
putative periplasmic binding protein/laci transcriptional regulatorSAMEA3499979_00267Not AvailableNegative294718 - 29579139289.6

Displaying genes 401 – 410 of 5143 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total