Klebsiella pneumoniae strain EuSCAPE_PL018

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PL018 is a pathogenic, Gram-negative bacterium that belongs to the Enterobacteriaceae family. It is characterized by its rod shape and the presence of flagella, which confer motility. This strain is a facultative anaerobe, allowing it to thrive in varying oxygen conditions, and it has an optimal growth temperature of 37°C, classifying it as mesophilic. The bacterium typically exists in a host-associated habitat and is considered free-living, highlighting its adaptability to different environments. It is a chemoheterotroph, deriving energy from organic compounds. The cell arrangement of EuSCAPE_PL018 can be observed in chains, pairs, and singles, which may influence its interactions with host organisms. Klebsiella pneumoniae strain EuSCAPE_PL018 has a broad host range, affecting various species, including humans (Homo sapiens), birds (Gallus gallus and Phasianidae), mammals (Sus scrofa and Canis lupus familiaris), and even aquatic species like Danio rerio. This versatility in host range can contribute to the bacterium’s ability to adapt and persist in different ecological niches. Clinically, the strain is associated with numerous health effects, including bacteremia, urinary tract infections, pneumonia, and a variety of other serious infections such as sepsis and meningitis. Its pathogenicity primarily affects humans, underscoring its significance in clinical microbiology. Overall, the ecological adaptability and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_PL018 emphasize the importance of monitoring this organism in healthcare settings to prevent and control infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PL018

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PL018
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PL018 genome assembly,

Gene Summary

Adenine Count

1131865 bp

Thymine Count

1134906 bp

Guanine Count

1538469 bp

Cytosine Count

1520301 bp

Genome Length

5325541 bp

Protein-coding Genes

4778 genes

Non-Coding Genes

328 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3499976_00154Not AvailableNegative154437 - 15498820956.0
uncharacterised proteinSAMEA3499976_00155Not AvailableNegative154960 - 15588635540.4
Holin proteinSAMEA3499976_00156Not AvailablePositive156800 - 1570157889.69
Phage lysozymeSAMEA3499976_00157Not AvailablePositive157015 - 15751218326.2
Hypothetical proteinSAMEA3499976_00158Not AvailablePositive157509 - 15785912728.3
Hypothetical proteinSAMEA3499976_00159Not AvailableNegative158935 - 1591357570.2
uncharacterised proteinSAMEA3499976_00160Not AvailablePositive159312 - 1594765866.04
Gp61SAMEA3499976_00161Not AvailablePositive159774 - 16009111627.8
Gp62SAMEA3499976_00162Not AvailablePositive160088 - 16051915250.0
Putative small terminase subunitSAMEA3499976_00163Not AvailablePositive160768 - 16120215585.8

Displaying genes 21 – 30 of 5106 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total