Klebsiella pneumoniae strain EuSCAPE_PL012

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PL012 is a gram-negative, rod-shaped bacterium that displays a diverse range of pathogenic effects in humans and various hosts, including Homo sapiens, Gallus gallus, and Danio rerio. This strain is a facultative anaerobe, enabling it to thrive in both aerobic and anaerobic environments, and it is classified as a chemoheterotroph, utilizing organic compounds for energy. EuSCAPE_PL012 typically exists in chains, pairs, or as singles, demonstrating a versatile cell arrangement. It possesses flagella, contributing to its mobility. This strain is mesophilic, with an optimal growth temperature of 37°C, which aligns with the human body temperature, suggesting an adaptation to host-associated habitats. The pathogenicity of Klebsiella pneumoniae strain EuSCAPE_PL012 is notable, as it is associated with a variety of serious health conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis. These infections pose significant health risks, particularly in vulnerable populations, such as neonates and individuals with compromised immune systems. Klebsiella pneumoniae's ability to infect a wide range of hosts indicates its ecological versatility and underscores its importance in both human health and veterinary contexts. The strain’s free-living biotic relationship further emphasizes its adaptability to various ecological niches. Understanding the traits of EuSCAPE_PL012 can aid in developing targeted strategies for managing infections and mitigating its impact on health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PL012

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PL012
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PL012 genome assembly,

Gene Summary

Adenine Count

0 bp

Thymine Count

0 bp

Guanine Count

0 bp

Cytosine Count

0 bp

Genome Length

0 bp

Protein-coding Genes

4933 genes

Non-Coding Genes

288 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribonucleotide reductase of class ib (aerobic) subunit alphaSAMEA3499948_00607Not AvailableNegative643273 - 64541480153.3
ribonucleotide reduction protein nrdiSAMEA3499948_00608Not AvailableNegative645387 - 64579715322.4
glutaredoxin-like protein nrdhSAMEA3499948_00609Not AvailableNegative645794 - 6460399254.15
carboxymuconolactone decarboxylase family proteinSAMEA3499948_00610Not AvailableNegative646223 - 64665415817.0
gntr family transcriptional regulatorSAMEA3499948_00611Not AvailablePositive646743 - 64809550249.7
membrane proteinSAMEA3499948_00612Not AvailableNegative648239 - 64858612578.7
protein of uncharacterised function (duf2002)SAMEA3499948_00613Not AvailablePositive648736 - 64909813634.3
inner membrane proteinSAMEA3499948_00614Not AvailableNegative649184 - 64963316865.9
dna-binding proteinSAMEA3499948_00615Not AvailablePositive650362 - 65076315179.2
uncharacterised proteinSAMEA3499948_00616Not AvailableNegative650836 - 6510156410.56

Displaying genes 801 – 810 of 5221 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total