Klebsiella pneumoniae strain EuSCAPE_SK031

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SK031 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe, allowing it to thrive in various oxygen conditions. This strain is a chemoheterotroph, obtaining energy from organic compounds, and it exhibits mobility due to the presence of flagella. The bacterium is typically found in host-associated environments, indicating its close relationship with various organisms, including humans (Homo sapiens) and several animal species such as Gallus gallus, Sus scrofa, and Canis lupus familiaris. EuSCAPE_SK031 has a mesophilic temperature range, with an optimal growth temperature of 37°C. It possesses a single replicon and is characterized by a double membrane structure, consistent with its classification within the Enterobacteriaceae family. The strain exists in various arrangements, including chains, pairs, and singles. This bacterium is notably pathogenic to humans, causing a wide array of serious health conditions, such as bacteremia, urinary tract infections, pneumonia, and sepsis. The diverse range of diseases associated with Klebsiella pneumoniae underscores its significant impact on human health, particularly in hospital settings, where it can lead to severe bloodstream infections and complications in vulnerable populations, including neonates. The ecological insight from the pathogenicity of Klebsiella pneumoniae strain EuSCAPE_SK031 suggests that its adaptability and ability to thrive in various hosts highlight its potential as a persistent opportunistic pathogen in both community and healthcare environments. Its presence across multiple animal hosts also raises questions about transmission dynamics and the role of environmental reservoirs in the spread of antibiotic-resistant strains.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SK031

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SK031
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SK031 genome assembly,

Gene Summary

Adenine Count

1197664 bp

Thymine Count

1198480 bp

Guanine Count

1609057 bp

Cytosine Count

1595013 bp

Genome Length

5600214 bp

Protein-coding Genes

5095 genes

Non-Coding Genes

268 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
inner membrane metabolite transport protein yhjeSAMEA3498967_02828Not AvailablePositive2982408 - 298373047028.8
asma family proteinSAMEA3498967_02829Not AvailableNegative2983768 - 298581974441.8
ketodeoxygluconokinaseSAMEA3498967_02830Not AvailablePositive2986014 - 298694333957.1
protein yhjj, putative peptidaseSAMEA3498967_02831Not AvailableNegative2986998 - 298850055758.5
aerobic c4-dicarboxylate transporterSAMEA3498967_02832Not AvailableNegative2988720 - 299000645373.0
protein yhjkSAMEA3498967_02833Not AvailableNegative2990163 - 299216975004.3
cellulose synthase operon protein cSAMEA3498967_02834Not AvailableNegative2992412 - 2995888127044.0
endoglucanaseSAMEA3498967_02835Not AvailableNegative2995870 - 299697940903.4
cellulose synthase regulator proteinSAMEA3498967_02836Not AvailableNegative2996983 - 299930785149.3
cellulose synthase catalytic subunitSAMEA3498967_02837Not AvailableNegative2999339 - 300195799317.2

Displaying genes 3011 – 3020 of 5363 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total