Klebsiella pneumoniae strain EuSCAPE_CZ025

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_CZ025 is a Gram-negative, rod-shaped bacterium classified as a chemoheterotroph. It exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. This strain is capable of movement due to the presence of flagella and typically arranges itself in chains, pairs, or singles. With an optimal growth temperature of 37°C, EuSCAPE_CZ025 falls within the mesophilic temperature range. Notably, Klebsiella pneumoniae strain EuSCAPE_CZ025 has a diverse range of biotic relationships, being free-living and associated with multiple hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other metazoans and plant species. This broad host range highlights its ecological versatility. Clinically, Klebsiella pneumoniae is recognized for its pathogenicity in humans, leading to a variety of health issues, including bacteremia, urinary tract infections, pneumonia, and several other serious infections such as sepsis and neonatal sepsis. The strain’s ability to cause diverse and severe infections emphasizes its significance in healthcare settings, particularly in relation to antibiotic resistance. Overall, the ecological adaptability and pathogenic potential of Klebsiella pneumoniae strain EuSCAPE_CZ025 suggest a complex interaction with both hosts and environments, reflecting its role in public health and disease ecology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_CZ025

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_CZ025
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_CZ025 genome assembly,

Gene Summary

Adenine Count

1190716 bp

Thymine Count

1191188 bp

Guanine Count

1591263 bp

Cytosine Count

1600928 bp

Genome Length

5574095 bp

Protein-coding Genes

5056 genes

Non-Coding Genes

290 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
conjugal transfer pilus assembly protein trahSAMEA3499021_04919Not AvailableNegative5178506 - 517987650250.4
conjugal transfer protein trbfSAMEA3499021_04920Not AvailableNegative5179863 - 518029116805.6
conjugal transfer protein trbbSAMEA3499021_04921Not AvailableNegative5180284 - 518085620459.4
conjugal transfer pilin chaperone traqSAMEA3499021_04922Not AvailableNegative5180828 - 51810678928.05
conjugal pilus assembly protein trafSAMEA3499021_04923Not AvailableNegative5181078 - 518183028297.0
uncharacterised proteinSAMEA3499021_04924Not AvailableNegative5181851 - 518217712597.2
uncharacterised proteinSAMEA3499021_04925Not AvailableNegative5182223 - 51824087094.23
conjugal transfer protein trbeSAMEA3499021_04926Not AvailableNegative5182405 - 51826418996.01
type-f conjugative transfer system mating-pair stabilization protein tranSAMEA3499021_04927Not AvailableNegative5182673 - 518467972942.3
cconjugal transfer pilus assembly protein trbcSAMEA3499021_04928Not AvailableNegative5184676 - 518531423659.4

Displaying genes 4971 – 4980 of 5346 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total