Klebsiella pneumoniae strain EuSCAPE_CZ031

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_CZ031 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. This strain is capable of existing in various arrangements, including chains, pairs, and singles, and possesses flagella, indicating motility. It thrives optimally at 37°C, placing it within the mesophilic temperature range. K. pneumoniae EuSCAPE_CZ031 is associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and various other Metazoa and Viridiplantae, suggesting its adaptability to different biological environments. This strain is known for its pathogenicity in humans, being implicated in numerous health conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis. The extensive list of infections associated with this bacterium highlights its significant role as a human pathogen, particularly in causing severe diseases like pyogenic liver abscesses and neonatal sepsis. Additionally, K. pneumoniae EuSCAPE_CZ031 is characterized by having a single replicon and a double membrane structure, typical of Gram-negative bacteria. Its nonsporulating nature further indicates its reliance on host environments for survival and reproduction. The ecological insight from this strain's diverse host associations underscores the interplay between pathogenicity and environmental adaptability. Such versatility may contribute to its spread in clinical settings and highlight the importance of monitoring and controlling infections caused by this opportunistic pathogen in both human and veterinary medicine.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_CZ031

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_CZ031
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_CZ031 genome assembly,

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4911 genes

Non-Coding Genes

342 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
LysozymeSAMEA3499027_02971Not AvailablePositive3177633 - 317813018469.9
Lysb family lysis regulatory proteinSAMEA3499027_02972Not AvailablePositive3178127 - 317855816121.5
Tail proteinSAMEA3499027_02973Not AvailablePositive3178654 - 317912117600.1
Virion morphogenesis proteinSAMEA3499027_02974Not AvailablePositive3179114 - 317956316980.7
AttrNot AvailableNot AvailablePositive3179849 - 3179860Not Available
Hypothetical proteinSAMEA3499027_02975Not AvailablePositive3179891 - 318093440636.3
Baseplate assembly protein vSAMEA3499027_02976Not AvailablePositive3181166 - 318191826641.7
Baseplate assembly proteinSAMEA3499027_02977Not AvailablePositive3181915 - 318226212719.4
Baseplate assembly protein jSAMEA3499027_02978Not AvailablePositive3182267 - 318317532445.4
Tail proteinSAMEA3499027_02979Not AvailablePositive3183168 - 318378523213.4

Displaying genes 71 – 80 of 5250 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total