Klebsiella pneumoniae strain EuSCAPE_CZ013

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_CZ013 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, relying on chemoheterotrophy for energy. This strain is characterized by its ability to form chains, pairs, and singles, and possesses flagella, indicating motility. Optimal growth occurs at 37°C, placing it within the mesophilic temperature range. EuSCAPE_CZ013 is primarily host-associated, with a diverse range of potential hosts including Homo sapiens, various avian species, and several mammals such as Canis lupus familiaris and Sus scrofa. This broad host range highlights the strain's ecological versatility and potential for cross-species transmission. The pathogenicity of K. pneumoniae EuSCAPE_CZ013 is significant, as it is associated with a wide array of health effects in humans, including but not limited to bacteremia, urinary tract infections, pneumonia, and sepsis. The strain is nonsporulating and has a biotic relationship classified as free-living, suggesting that while it can thrive in various environments, it is also capable of causing opportunistic infections, particularly in immunocompromised individuals. Given its pathogenic potential and adaptability to different hosts, K. pneumoniae EuSCAPE_CZ013 serves as a critical subject of study in understanding the dynamics of bacterial infections and antibiotic resistance. The strain's ability to infect multiple host species underscores the importance of monitoring its spread and the implications for public health, especially in healthcare settings where multidrug-resistant strains are a growing concern.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_CZ013

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_CZ013
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_CZ013 genome assembly,

Gene Summary

Adenine Count

1185292 bp

Thymine Count

1187876 bp

Guanine Count

1576074 bp

Cytosine Count

1604676 bp

Genome Length

5553918 bp

Protein-coding Genes

5070 genes

Non-Coding Genes

275 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive2813979 - 2813990Not Available
Hypothetical proteinSAMEA3499009_02709Not AvailablePositive2826061 - 28263099396.2
Hypothetical proteinSAMEA3499009_02710Not AvailableNegative2826532 - 282681610808.9
Hypothetical proteinSAMEA3499009_02711Not AvailableNegative2826921 - 28271307647.79
Concanavalin a-like lectin/glucanase superfamily proteinSAMEA3499009_02712Not AvailableNegative2827127 - 282785825618.3
Tail fiber proteinSAMEA3499009_02713Not AvailableNegative2827869 - 2830892110779.0
uncharacterised proteinSAMEA3499009_02714Not AvailableNegative2830948 - 28311457392.66
Tail fiber proteinSAMEA3499009_02715Not AvailableNegative2831145 - 283201127285.6
Hypothetical proteinSAMEA3499009_02716Not AvailableNegative2832011 - 283278428812.8
Gp61 putative baseplate proteinSAMEA3499009_02717Not AvailableNegative2832781 - 283397740803.9

Displaying genes 71 – 80 of 5345 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total