Klebsiella pneumoniae strain EuSCAPE_CZ015

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_CZ015 is a Gram-negative, rod-shaped bacterium known for its pathogenicity in humans. This strain is a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments, and it typically prefers an optimal growth temperature of 37°C, falling within the mesophilic temperature range. The bacterium exhibits a motile nature, aided by the presence of flagella, and can be found in various cellular arrangements, including chains, pairs, and singles. EuSCAPE_CZ015 is classified as a chemoheterotroph, deriving its energy from organic compounds. It has a complex ecological relationship, being free-living but also associated with a diverse array of hosts, including Homo sapiens, various animals (such as Gallus gallus, Sus scrofa, and Canis lupus familiaris), and even certain plants (Viridiplantae). This strain is notable for its involvement in a variety of health complications, including bacteremia, urinary tract infections, pneumonia, and liver abscesses, among others. The range of infections it can cause underscores its significant pathogenic potential in human health. The presence of Klebsiella pneumoniae in such a wide variety of hosts suggests its adaptability and resilience in different ecological niches. Its role in both free-living and pathogenic contexts highlights the complexity of microbial interactions within environments shared by multiple species, as well as the potential for zoonotic transmission and the impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_CZ015

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_CZ015
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_CZ015 genome assembly,

Gene Summary

Adenine Count

1184302 bp

Thymine Count

1180791 bp

Guanine Count

1573570 bp

Cytosine Count

1585927 bp

Genome Length

5524590 bp

Protein-coding Genes

5081 genes

Non-Coding Genes

84 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
lysr family transcriptional regulatorSAMEA3499011_00106Not AvailablePositive113755 - 11464232861.7
l-asparagine permeaseSAMEA3499011_00107Not AvailablePositive114832 - 11628652431.2
outer membrane lipoproteinSAMEA3499011_00108Not AvailableNegative116337 - 1165587872.46
putative receptorSAMEA3499011_00109Not AvailableNegative116727 - 11778838329.6
tonb-dependent receptor yncdSAMEA3499011_00110Not AvailablePositive118047 - 12015277097.7
amidohydrolaseSAMEA3499011_00111Not AvailablePositive120350 - 12205661795.4
protein of uncharacterised function (duf406)SAMEA3499011_00112Not AvailableNegative122154 - 12245310620.6
ribonucleoside hydrolase 1SAMEA3499011_00113Not AvailablePositive122735 - 12367033886.1
oxidoreductase yncbSAMEA3499011_00114Not AvailableNegative123733 - 12477037232.7
transcriptional regulatorSAMEA3499011_00115Not AvailableNegative124836 - 12541721558.8

Displaying genes 111 – 120 of 5165 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total