Klebsiella pneumoniae strain EuSCAPE_SK046

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SK046 is a gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and a chemoheterotroph. This strain can exist in various cellular arrangements, including chains, pairs, and singles. It is motile due to the presence of flagella and has an optimal growth temperature of 37°C, categorizing it as mesophilic. The strain is notable for its pathogenicity in humans, where it is associated with a range of serious health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis. Additionally, it has been linked to various infections such as intra-abdominal infections, meningitis, and pyogenic liver abscesses. Its ability to infect multiple hosts, including species from Metazoa, Viridiplantae, and various animals such as Homo sapiens, Gallus gallus, and Canis lupus familiaris, highlights its ecological versatility and potential for cross-species transmission. Klebsiella pneumoniae strain EuSCAPE_SK046 is nonsporulating and possesses a single replicon and two membranes, which are characteristic features of Gram-negative bacteria. The strain's free-living biotic relationship suggests that it can thrive independently within diverse environments, potentially contributing to its pathogenic capabilities. Understanding the ecological dynamics of this strain is crucial, especially considering its role in human infections and its presence in multiple animal hosts, indicating a complex web of interactions that could influence public health and disease transmission pathways.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SK046

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SK046
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SK046 genome assembly,

Gene Summary

Adenine Count

1175572 bp

Thymine Count

1178295 bp

Guanine Count

1592071 bp

Cytosine Count

1565774 bp

Genome Length

5511712 bp

Protein-coding Genes

5045 genes

Non-Coding Genes

245 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Tail proteinSAMEA3498994_03702Not AvailablePositive3848539 - 384963940956.7
Hypothetical proteinSAMEA3498994_03703Not AvailablePositive3849731 - 38499497964.55
Gp245SAMEA3498994_04200Not AvailableNegative4403119 - 440392830480.2
Abc transporterSAMEA3498994_04201Not AvailableNegative4403930 - 440492237597.8
peptide transport system permease protein sapcSAMEA3498994_04202Not AvailableNegative4404922 - 440581231661.4
IntegraseSAMEA3498994_04203Not AvailablePositive4405959 - 440717646870.8
Adenine specific methyltransferaseSAMEA3498994_04204Not AvailableNegative4407384 - 440804624719.3
Hypothetical proteinSAMEA3498994_04205Not AvailableNegative4408043 - 440847116076.6
ExonucleaseSAMEA3498994_04206Not AvailableNegative4408468 - 440914825855.8
Putative phage recombination proteinSAMEA3498994_04207Not AvailableNegative4409434 - 441027931193.1

Displaying genes 131 – 140 of 5290 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total