Klebsiella pneumoniae strain EuSCAPE_CZ012

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_CZ012 is a Gram-negative, rod-shaped bacterium recognized for its pathogenicity in humans and several other hosts, including mammals and birds. This strain is facultatively anaerobic, allowing it to thrive in both aerobic and anaerobic environments, and is categorized as a chemoheterotroph, utilizing organic compounds for energy. The cell arrangement of EuSCAPE_CZ012 can be observed in chains, pairs, and singles, and it is motile due to the presence of flagella. This strain has an optimal growth temperature of 37°C, fitting within the mesophilic range. It contains a single replicon and is characterized by a double membrane structure. Klebsiella pneumoniae strain EuSCAPE_CZ012 is associated with a variety of health effects, particularly in humans, where it can cause conditions such as bacteremia, pneumonia, urinary tract infections, and meningitis, among others. These infections highlight its significant role as a human pathogen, capable of causing severe health complications. Ecologically, this strain demonstrates a free-living biotic relationship, suggesting it can thrive independently in various environments. Its broad host range, which includes Homo sapiens, Gallus gallus, and other metazoans, indicates its adaptability and potential for transmission across species. The ability of Klebsiella pneumoniae to inhabit diverse ecological niches and its association with a wide range of infections underscore the importance of monitoring and understanding its pathogenic mechanisms in both clinical and environmental contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_CZ012

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_CZ012
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_CZ012 genome assembly,

Gene Summary

Adenine Count

1159383 bp

Thymine Count

1162344 bp

Guanine Count

1581908 bp

Cytosine Count

1545855 bp

Genome Length

5449490 bp

Protein-coding Genes

4969 genes

Non-Coding Genes

193 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3499008_00216Not AvailablePositive225072 - 22554518276.8
Hypothetical proteinSAMEA3499008_00217Not AvailablePositive225532 - 22600817364.3
Hypothetical proteinSAMEA3499008_00218Not AvailablePositive226021 - 22640114171.1
Tail proteinSAMEA3499008_00219Not AvailablePositive226398 - 229475111360.0
Tail fiber proteinSAMEA3499008_00220Not AvailablePositive229553 - 23131663490.9
AttrNot AvailableNot AvailablePositive236314 - 236334Not Available
AttlNot AvailableNot AvailablePositive2187455 - 2187500Not Available
IntegraseSAMEA3499008_02073Not AvailableNegative2187515 - 218867844316.4
Hypothetical proteinSAMEA3499008_02074Not AvailableNegative2188892 - 21891108341.86
Hypothetical proteinSAMEA3499008_02075Not AvailableNegative2189107 - 21892986775.13

Displaying genes 41 – 50 of 5162 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total