Klebsiella pneumoniae strain EuSCAPE_CZ004

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_CZ004 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle, allowing it to thrive in varying oxygen conditions. It can be found in host-associated environments, where it displays mobility due to the presence of flagella. This strain is classified as a chemoheterotroph, utilizing organic compounds for energy. Optimal growth occurs at 37°C, placing it within the mesophilic temperature range. The organism has a simple genetic structure characterized by a single replicon and is surrounded by two membranes, typical of Gram-negative bacteria. In terms of cellular arrangement, K. pneumoniae can exist in chains, pairs, or as single cells. EuSCAPE_CZ004 is known to have a diverse range of hosts, including humans (Homo sapiens), domestic animals such as chickens (Gallus gallus) and pigs (Sus scrofa), as well as various other metazoans and plants. Its pathogenicity is a significant concern in human health, as it is associated with numerous serious infections, including bacteremia, urinary tract infections, pneumonia, and sepsis. This strain's ability to infect multiple hosts highlights its ecological versatility and potential as a pathogen in both human and veterinary medicine. The presence of K. pneumoniae in various environments suggests its role in the microbial dynamics of host-associated habitats, where it can impact health and disease outcomes across species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_CZ004

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_CZ004
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_CZ004 genome assembly,

Gene Summary

Adenine Count

1130858 bp

Thymine Count

1134994 bp

Guanine Count

1531599 bp

Cytosine Count

1519946 bp

Genome Length

5317397 bp

Protein-coding Genes

4889 genes

Non-Coding Genes

189 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
LysozymeSAMEA3499000_03184Not AvailablePositive3318321 - 331883018469.4
Hypothetical proteinSAMEA3499000_03185Not AvailablePositive3318835 - 331921814021.8
Outer-membrane spanin componentSAMEA3499000_03186Not AvailablePositive3319486 - 331977610382.6
Tail proteinSAMEA3499000_03187Not AvailablePositive3319739 - 332017015919.8
Virion morphogenesis proteinSAMEA3499000_03188Not AvailablePositive3320163 - 332060917426.2
Hypothetical proteinSAMEA3499000_03189Not AvailableNegative3320606 - 332129826276.5
Baseplate assembly protein vSAMEA3499000_03190Not AvailablePositive3321393 - 332196520657.2
Baseplate assembly proteinSAMEA3499000_03191Not AvailablePositive3321962 - 332232413243.9
Baseplate assembly protein jSAMEA3499000_03192Not AvailablePositive3322311 - 332321932702.6
Tail protein iSAMEA3499000_03193Not AvailablePositive3323212 - 332381122453.5

Displaying genes 41 – 50 of 5078 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total