Klebsiella pneumoniae strain EuSCAPE_SK030

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SK030 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and a chemoheterotroph. This strain can be found in a host-associated habitat and exhibits a diverse range of hosts, including Homo sapiens, various livestock species such as Gallus gallus and Sus scrofa, and other metazoans like Danio rerio and Canis lupus familiaris. EuSCAPE_SK030 is known for its pathogenic potential in humans, being associated with a variety of severe health effects such as bacteremia, urinary tract infections, pneumonia, and sepsis. The strain is implicated in both community-acquired and hospital-associated infections, including neonatal sepsis and pulmonary infections. Its ability to cause infections in multiple hosts underscores its adaptability and pathogenicity. The bacterium displays a versatile cell arrangement, existing in chains, pairs, or as single cells, and possesses flagella, indicating mobility. It thrives optimally at 37°C, placing it within a mesophilic temperature range. Importantly, Klebsiella pneumoniae is nonsporulating and has a single replicon with a double-membrane structure, typical of Gram-negative bacteria. The ecological implications of Klebsiella pneumoniae strain EuSCAPE_SK030 illustrate its role as a free-living organism capable of colonizing various environments and hosts. Its association with serious infections highlights the need for continued surveillance and research to understand its epidemiology and impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SK030

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SK030
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SK030 genome assembly,

Gene Summary

Adenine Count

1202351 bp

Thymine Count

1198072 bp

Guanine Count

1599000 bp

Cytosine Count

1609190 bp

Genome Length

5608613 bp

Protein-coding Genes

5071 genes

Non-Coding Genes

320 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
tryptophanyl-trna synthetaseSAMEA3500098_02974Not AvailableNegative3083739 - 308474337507.0
phosphoglycolate phosphataseSAMEA3500098_02975Not AvailableNegative3084736 - 308549727465.8
ribulose-phosphate 3-epimeraseSAMEA3500098_02976Not AvailableNegative3085490 - 308616724380.4
methyl-directed repair dna adenine methylaseSAMEA3500098_02977Not AvailableNegative3086185 - 308701232002.2
sporulation domain-containing proteinSAMEA3500098_02978Not AvailableNegative3087091 - 308835044595.7
3-dehydroquinate synthaseSAMEA3500098_02979Not AvailableNegative3088462 - 308955639187.5
shikimate kinaseSAMEA3500098_02980Not AvailableNegative3089612 - 309013319487.1
outer membrane porin hofqSAMEA3500098_02981Not AvailableNegative3090404 - 309164845125.6
type iv pilus biogenesis protein piloSAMEA3500098_02982Not AvailableNegative3091954 - 309238215633.1
type iv pilus biogenesis protein pilnSAMEA3500098_02983Not AvailableNegative3092372 - 309290519952.2

Displaying genes 3161 – 3170 of 5391 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total