Klebsiella pneumoniae strain EuSCAPE_SK030

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SK030 is a Gram-negative, rod-shaped bacterium characterized as a facultative anaerobe and a chemoheterotroph. This strain can be found in a host-associated habitat and exhibits a diverse range of hosts, including Homo sapiens, various livestock species such as Gallus gallus and Sus scrofa, and other metazoans like Danio rerio and Canis lupus familiaris. EuSCAPE_SK030 is known for its pathogenic potential in humans, being associated with a variety of severe health effects such as bacteremia, urinary tract infections, pneumonia, and sepsis. The strain is implicated in both community-acquired and hospital-associated infections, including neonatal sepsis and pulmonary infections. Its ability to cause infections in multiple hosts underscores its adaptability and pathogenicity. The bacterium displays a versatile cell arrangement, existing in chains, pairs, or as single cells, and possesses flagella, indicating mobility. It thrives optimally at 37°C, placing it within a mesophilic temperature range. Importantly, Klebsiella pneumoniae is nonsporulating and has a single replicon with a double-membrane structure, typical of Gram-negative bacteria. The ecological implications of Klebsiella pneumoniae strain EuSCAPE_SK030 illustrate its role as a free-living organism capable of colonizing various environments and hosts. Its association with serious infections highlights the need for continued surveillance and research to understand its epidemiology and impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SK030

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SK030
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SK030 genome assembly,

Gene Summary

Adenine Count

1202351 bp

Thymine Count

1198072 bp

Guanine Count

1599000 bp

Cytosine Count

1609190 bp

Genome Length

5608613 bp

Protein-coding Genes

5071 genes

Non-Coding Genes

320 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
multidrug abc transporterSAMEA3500098_01654Not AvailableNegative1707739 - 170866534584.1
carbonic anhydraseSAMEA3500098_01655Not AvailablePositive1708850 - 170951225173.3
hypoxanthine-guanine phosphoribosyltransferaseSAMEA3500098_01656Not AvailableNegative1709572 - 171010820123.3
glucose dehydrogenaseSAMEA3500098_01657Not AvailablePositive1710313 - 171270386426.9
multicopper oxidase type 3SAMEA3500098_01658Not AvailableNegative1712787 - 171438557893.0
chaperone lipoprotein yaccSAMEA3500098_01659Not AvailablePositive1714519 - 171487813376.1
uncharacterised proteinSAMEA3500098_01660Not AvailablePositive1715126 - 171553614942.9
fkbp-type peptidyl-prolyl cis-trans isomerase fkpaSAMEA3500098_01661Not AvailablePositive1715533 - 171637530007.6
transposase is3/is911 family proteinSAMEA3500098_01662Not AvailablePositive1716424 - 171674112146.6
integrase catalytic subunitSAMEA3500098_01663Not AvailablePositive1716738 - 171761632930.5

Displaying genes 1911 – 1920 of 5391 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total