Klebsiella pneumoniae strain EuSCAPE_SK033

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SK033 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and capable of mobility due to the presence of flagella. It is a chemoheterotroph, using organic compounds as energy sources, and typically found in chains, pairs, or as singles. The strain thrives optimally at 37°C, indicating its mesophilic nature. This strain is associated with a variety of hosts, including Homo sapiens and various animal species such as Gallus gallus (chickens) and Sus scrofa (pigs). Its broad host range suggests a high level of ecological adaptability. EuSCAPE_SK033 is known for its pathogenicity in humans, causing a range of significant health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Klebsiella pneumoniae's ability to inhabit multiple hosts and its association with serious infections highlight its potential impact on public health and veterinary medicine. Its presence in diverse environments underscores the importance of monitoring this pathogen in both clinical and ecological contexts. The strain's pathogenic effects are a reminder of the complex interactions between humans, animals, and the microbial world, emphasizing the need for careful management and understanding of antibiotic resistance and transmission pathways.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SK033

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SK033
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SK033 genome assembly,

Gene Summary

Adenine Count

1164230 bp

Thymine Count

1165593 bp

Guanine Count

1568977 bp

Cytosine Count

1560363 bp

Genome Length

5459163 bp

Protein-coding Genes

4991 genes

Non-Coding Genes

242 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Amber mutation-suppressing proteinSAMEA3498969_03153Not AvailableNegative3337571 - 333813721200.0
Dna-binding transcriptional regulatorSAMEA3498969_03154Not AvailableNegative3338155 - 33384009188.91
Head size determination protein sidSAMEA3498969_03155Not AvailableNegative3338397 - 333913427210.3
Transcriptional regulatorSAMEA3498969_03156Not AvailablePositive3339695 - 33399619737.63
Putative ci repressorSAMEA3498969_03157Not AvailablePositive3340312 - 33405067109.72
uncharacterised proteinSAMEA3498969_03158Not AvailablePositive3340503 - 33407308577.31
Hypothetical proteinSAMEA3498969_03159Not AvailablePositive3340727 - 334104711761.5
Dna primaseSAMEA3498969_03160Not AvailablePositive3341062 - 334339584620.4
AttrNot AvailableNot AvailablePositive3343937 - 3343950Not Available
TransposaseSAMEA3498969_03161Not AvailablePositive3344141 - 334440710280.5

Displaying genes 61 – 70 of 5233 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total