Klebsiella pneumoniae strain EuSCAPE_SK022

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SK022 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, functioning as a chemoheterotroph. This strain is capable of existing in various arrangements, including chains, pairs, and singles, and possesses flagella, indicating mobility. Its optimal growth temperature is 37°C, and it thrives within a mesophilic temperature range. K. pneumoniae strain EuSCAPE_SK022 is associated with multiple hosts, including humans (Homo sapiens) and various animals such as chickens (Gallus gallus), fish (Danio rerio), and mammals like pigs (Sus scrofa) and dogs (Canis lupus familiaris). Its biotic relationship is categorized as free-living, suggesting an adaptability to diverse ecological niches. This strain is notable for its pathogenic potential in humans, where it is implicated in a wide range of health issues, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The bacterium's ability to cause severe infections highlights its significance in clinical microbiology and public health. The presence of K. pneumoniae strain EuSCAPE_SK022 in various host species points to its ecological versatility and potential for zoonotic transmission. This adaptability underscores the importance of monitoring such strains in both human and animal health contexts, as they may serve as reservoirs for pathogenicity and antimicrobial resistance, impacting broader ecosystems and public health initiatives.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SK022

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SK022
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SK022 genome assembly,

Gene Summary

Adenine Count

1113255 bp

Thymine Count

1117575 bp

Guanine Count

1513340 bp

Cytosine Count

1509044 bp

Genome Length

5253214 bp

Protein-coding Genes

4752 genes

Non-Coding Genes

279 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3500090_03275Not AvailablePositive3441545 - 344197316076.6
Adenine specific methyltransferaseSAMEA3500090_03276Not AvailablePositive3441970 - 344263224719.3
IntegraseSAMEA3500090_03277Not AvailableNegative3442840 - 344405746870.8
peptide transport system permease protein sapcSAMEA3500090_03278Not AvailablePositive3444204 - 344509431661.4
Abc transporterSAMEA3500090_03279Not AvailablePositive3445094 - 344608637597.8
Gp245SAMEA3500090_03280Not AvailablePositive3446088 - 344689730480.2
Tail proteinSAMEA3500090_04094Not AvailablePositive4336487 - 433716725125.2
Tail sheath proteinSAMEA3500090_04095Not AvailablePositive4337278 - 433845942329.2
Major tail tube proteinSAMEA3500090_04096Not AvailablePositive4338473 - 433898818826.5
Tail assembly proteinSAMEA3500090_04097Not AvailablePositive4339049 - 43393249837.23

Displaying genes 71 – 80 of 5031 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total