Klebsiella pneumoniae strain EuSCAPE_SK006

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SK006 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. It is a chemoheterotroph, deriving its energy from organic compounds. This strain exhibits a diverse cell arrangement, forming chains, pairs, and singles, and possesses flagella, contributing to its motility. It is classified as mesophilic, with an optimal growth temperature of 37°C. EuSCAPE_SK006 is notably associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and various species across Metazoa, Viridiplantae, and other groups such as Canis lupus familiaris and Sus scrofa. This versatility in host associations underlines its ecological adaptability and potential for zoonotic transmission. The strain is linked to several significant health effects, primarily in humans, causing conditions such as bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Its pathogenicity is a considerable concern in clinical settings, where it can lead to severe outcomes like septicemia and neonatal sepsis, among others. As a nonsporulating organism with a single replicon and a double membrane structure, K. pneumoniae EuSCAPE_SK006 exemplifies characteristics typical of many Enterobacteriaceae. Understanding its biotic relationships, particularly its free-living nature, highlights its role in both human health and environmental contexts, emphasizing the need for vigilance in monitoring its spread and impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SK006

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SK006
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SK006 genome assembly,

Gene Summary

Adenine Count

1201331 bp

Thymine Count

1202500 bp

Guanine Count

1611150 bp

Cytosine Count

1601917 bp

Genome Length

5616898 bp

Protein-coding Genes

5084 genes

Non-Coding Genes

313 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttrNot AvailableNot AvailablePositive1452215 - 1452227Not Available
uncharacterised proteinSAMEA3500074_01380Not AvailablePositive1452944 - 145373530189.6
Portal proteinSAMEA3500074_01381Not AvailableNegative1453732 - 145447228002.7
AttlNot AvailableNot AvailablePositive3494727 - 3494738Not Available
IntegraseSAMEA3500074_03277Not AvailablePositive3495961 - 349718746700.5
uncharacterised proteinSAMEA3500074_03278Not AvailablePositive3497280 - 349822136075.8
Transcriptional regulatorSAMEA3500074_03279Not AvailablePositive3498403 - 349868711198.2
RoiSAMEA3500074_03280Not AvailablePositive3498698 - 349947728437.3
uncharacterised proteinSAMEA3500074_03281Not AvailablePositive3499461 - 350019827327.9
uncharacterised proteinSAMEA3500074_03282Not AvailablePositive3500191 - 35003797224.61

Displaying genes 21 – 30 of 5397 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total