Klebsiella pneumoniae strain EuSCAPE_SK011

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SK011 is a Gram-negative, rod-shaped bacterium that is facultatively anaerobic and exhibits mobility due to the presence of flagella. This strain is categorized as a chemoheterotroph, relying on organic compounds for energy. It typically thrives at an optimal temperature of 37°C and falls within the mesophilic temperature range. This bacterium is host-associated, with a diverse range of potential hosts that include Homo sapiens (humans), Gallus gallus (chickens), various Metazoa, Viridiplantae (plants), Danio rerio (zebrafish), Ovis aries (sheep), Phasianidae (pheasants), Sus scrofa (pigs), Aves (birds), Canis lupus familiaris (dogs), Amphibia (amphibians), and Equidae (horses). The biotic relationship of K. pneumoniae strain EuSCAPE_SK011 is classified as free-living, indicating its ability to exist independently in various environments. Klebsiella pneumoniae is known for its pathogenicity in humans, being associated with numerous health complications, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. It is also implicated in serious conditions such as sepsis, neonatal sepsis, and liver abscesses. The presence of multiple hosts suggests that this strain may have a broader ecological role, potentially facilitating the transfer of pathogens across species. This could have implications for public health and animal health, highlighting the importance of monitoring Klebsiella pneumoniae in both human and veterinary contexts. The strain's adaptability and pathogenic potential underscore its significance in microbial ecology and infectious disease.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SK011

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SK011
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SK011 genome assembly,

Gene Summary

Adenine Count

1172195 bp

Thymine Count

1169858 bp

Guanine Count

1569891 bp

Cytosine Count

1575890 bp

Genome Length

5487834 bp

Protein-coding Genes

4976 genes

Non-Coding Genes

306 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
putative virulence factorSAMEA3500079_03450Not AvailableNegative3573386 - 357492155358.1
oxidoreductase family, nad-bindingSAMEA3500079_03451Not AvailableNegative3575033 - 357595634201.9
g20.3SAMEA3500079_03452Not AvailableNegative3575960 - 357661324256.9
ribosomal-protein-s5p-alanine acetyltransferaseSAMEA3500079_03453Not AvailableNegative3576623 - 357724623908.7
multidrug resistance protein mdthSAMEA3500079_03454Not AvailablePositive3577437 - 357864543890.2
lipoprotein ycebSAMEA3500079_03455Not AvailablePositive3578759 - 357931920282.6
dihydroorotaseSAMEA3500079_03456Not AvailablePositive3579445 - 358049138792.7
dna-damage-inducible protein iSAMEA3500079_03457Not AvailablePositive3580564 - 35808159307.85
biofilm formation regulatory protein bsssSAMEA3500079_03458Not AvailablePositive3581118 - 35813729737.27
n-methyl-l-tryptophan oxidaseSAMEA3500079_03459Not AvailablePositive3581498 - 358261640350.5

Displaying genes 3571 – 3580 of 5282 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total