Klebsiella pneumoniae strain EuSCAPE_SK004

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SK004 is a Gram-negative, rod-shaped bacterium that exhibits a variety of notable traits. This strain is classified as a facultative anaerobe, allowing it to thrive in both oxygen-rich and oxygen-poor environments. It typically exists in chains, pairs, or as single cells, displaying mobility due to the presence of flagella. As a chemoheterotroph, it derives energy from organic compounds, and its optimal growth temperature is 37°C, placing it within the mesophilic range. EuSCAPE_SK004 is associated with a wide range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and various other metazoans and vertebrates. This broad host range highlights its ecological versatility and potential for transmission across species. The strain is free-living, indicating it can survive independently outside of a host. Pathogenically, Klebsiella pneumoniae strain EuSCAPE_SK004 is known to cause multiple health issues, particularly in humans. It is associated with conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain's ability to cause severe infections underscores its clinical significance, particularly in immunocompromised individuals. Understanding the traits of Klebsiella pneumoniae strain EuSCAPE_SK004 is crucial for addressing its impact on human health and developing strategies for infection control. Its adaptability and pathogenic potential highlight the need for ongoing surveillance and research in microbiology.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SK004

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SK004
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SK004 genome assembly,

Gene Summary

Adenine Count

1205175 bp

Thymine Count

1201054 bp

Guanine Count

1601025 bp

Cytosine Count

1614501 bp

Genome Length

5621755 bp

Protein-coding Genes

5092 genes

Non-Coding Genes

319 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
malate dehydrogenaseSAMEA3500072_02845Not AvailablePositive2979329 - 298026732428.3
outer membrane stress sensor protease degsSAMEA3500072_02846Not AvailableNegative2980404 - 298146237125.8
serine endoproteaseSAMEA3500072_02847Not AvailableNegative2981550 - 298291747243.3
cytochrome d ubiquinol oxidase subunit iiiSAMEA3500072_02848Not AvailableNegative2983091 - 298348915046.8
atpaseSAMEA3500072_02849Not AvailablePositive2983680 - 298480742498.3
50s ribosomal protein l13SAMEA3500072_02850Not AvailablePositive2985073 - 298550116110.6
30s ribosomal protein s9SAMEA3500072_02851Not AvailablePositive2985517 - 298590914857.1
stringent starvation protein aSAMEA3500072_02852Not AvailablePositive2986221 - 298685924191.2
clpxp protease specificity-enhancing factor / stringent starvation protein bSAMEA3500072_02853Not AvailablePositive2986863 - 298735717982.1
n-acetylmannosamine-6-phosphate 2-epimeraseSAMEA3500072_02854Not AvailablePositive2987482 - 298818624488.5

Displaying genes 3061 – 3070 of 5411 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total