Klebsiella pneumoniae strain EuSCAPE_SK003

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_SK003 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, allowing it to thrive in both aerobic and anaerobic environments. This strain is classified as a chemoheterotroph, utilizing organic compounds for energy. It is capable of mobility due to the presence of flagella and typically arranges itself in chains, pairs, or as singles. The organism has a mesophilic temperature range, with an optimal growth temperature of 37°C. EuSCAPE_SK003 is associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and various other metazoans and plants. This versatility in host association highlights its ecological adaptability. It is free-living, yet it exhibits significant pathogenicity in humans, being implicated in numerous health conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The strain is characterized by having a single replicon and two membranes, which is typical for Gram-negative bacteria. Notably, it does not undergo sporulation. The diverse health impacts associated with Klebsiella pneumoniae strain EuSCAPE_SK003 underscore its importance in both clinical settings and public health, presenting challenges in infection control due to its ability to cause severe infections across various host species. Understanding its ecological relationships and pathogenic potential is critical for developing effective treatment and prevention strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_SK003

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_SK003
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_SK003 genome assembly,

Gene Summary

Adenine Count

1174752 bp

Thymine Count

1182758 bp

Guanine Count

1595890 bp

Cytosine Count

1564247 bp

Genome Length

5517647 bp

Protein-coding Genes

5052 genes

Non-Coding Genes

243 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3500071_01622Not AvailablePositive1686345 - 16865367326.97
Terminase small subunitSAMEA3500071_01623Not AvailablePositive1686494 - 168685013284.7
Terminase large subunitSAMEA3500071_01624Not AvailablePositive1686834 - 168849562400.3
uncharacterised proteinSAMEA3500071_01625Not AvailablePositive1688498 - 16886897533.4
dna-binding protein fisSAMEA3500071_01626Not AvailableNegative1688843 - 168913911240.6
trna dihydrouridine synthase bSAMEA3500071_01627Not AvailableNegative1689164 - 169012935837.2
50s ribosomal protein l11 methyltransferaseSAMEA3500071_01628Not AvailableNegative1690487 - 169136831873.9
Hypothetical proteinSAMEA3500071_01629Not AvailableNegative1691380 - 169283151694.2
AttrNot AvailableNot AvailablePositive1697555 - 1697566Not Available
AttlNot AvailableNot AvailablePositive2514389 - 2514400Not Available

Displaying genes 21 – 30 of 5295 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total