Klebsiella pneumoniae strain EuSCAPE_FR051

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_FR051 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. It is characterized by its ability to form chains, pairs, and single cells and possesses flagella, indicating motility. The strain has a mesophilic temperature range, with an optimal growth temperature of 37°C, which aligns with the body temperature of many hosts. This strain is associated with various hosts, including Homo sapiens, Gallus gallus, and several other metazoan and plant species, highlighting its ecological versatility. It engages in free-living biotic relationships, which may contribute to its adaptation in diverse environments. Klebsiella pneumoniae EuSCAPE_FR051 is known for its pathogenicity in humans, where it can lead to a range of health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis. The presence of this bacterium in clinical settings underscores its significance as a human pathogen. The strain is nonsporulating and contains a single replicon within its double-membrane structure, which is typical for many Gram-negative bacteria. The ability of Klebsiella pneumoniae to thrive in various habitats and infect multiple hosts suggests a robust ecological adaptability that may facilitate its persistence in both environmental and clinical contexts. Understanding its pathogenic potential and environmental adaptability is crucial for developing effective strategies to manage infections caused by this bacterium.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_FR051

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_FR051
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_FR051 genome assembly,

Gene Summary

Adenine Count

1113949 bp

Thymine Count

1112942 bp

Guanine Count

1501113 bp

Cytosine Count

1509038 bp

Genome Length

5237042 bp

Protein-coding Genes

4755 genes

Non-Coding Genes

196 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3500036_00393Not AvailableNegative424535 - 42484311173.5
Hypothetical proteinSAMEA3500036_00394Not AvailableNegative425033 - 42559321471.8
Regulatory proteinSAMEA3500036_00395Not AvailablePositive425734 - 4259618172.79
Cii proteinSAMEA3500036_00396Not AvailablePositive425967 - 42653020700.4
Dna replication protein oSAMEA3500036_00397Not AvailablePositive426940 - 42780032724.8
Dna replication protein pSAMEA3500036_00398Not AvailablePositive427797 - 42851027261.9
Putative dna-binding proteinSAMEA3500036_00399Not AvailablePositive428503 - 42883812529.4
Chromosome partitioning protein gp35SAMEA3500036_00400Not AvailablePositive428831 - 42961628708.5
Hypothetical proteinSAMEA3500036_00401Not AvailablePositive429613 - 4298167891.74
Hypothetical proteinSAMEA3500036_00402Not AvailablePositive429809 - 4300488807.57

Displaying genes 61 – 70 of 4951 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total