Klebsiella pneumoniae strain EuSCAPE_FR052

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_FR052 is a significant pathogenic bacterium primarily associated with human hosts, although it is also found in various other organisms, including domestic animals and plants. This Gram-negative bacterium exhibits a rod shape and can be found in diverse arrangements, including chains, pairs, and singles. It is classified as a facultative anaerobe, meaning it can thrive in both aerobic and anaerobic environments, and it is identified as a chemoheterotroph, obtaining energy from organic compounds. EuSCAPE_FR052 is mobile due to the presence of flagella and prefers an optimal growth temperature of 37°C, fitting within the mesophilic temperature range. The bacterium has a complex cell structure, possessing two membranes and a single replicon, which is characteristic of many Gram-negative bacteria. This strain is known to cause a variety of health issues, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. Such infections can lead to severe complications, especially in immunocompromised individuals. The ecological insight from the traits of Klebsiella pneumoniae strain EuSCAPE_FR052 highlights its versatility and adaptability within various environments and hosts. Its ability to exist in diverse habitats, combined with its pathogenic potential, underscores the importance of monitoring this organism in both clinical and environmental microbiology contexts. The broad range of hosts indicates a significant role in the microbiota of diverse ecosystems, while its pathogenicity necessitates vigilance in public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_FR052

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_FR052
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_FR052 genome assembly,

Gene Summary

Adenine Count

1159980 bp

Thymine Count

1155671 bp

Guanine Count

1576838 bp

Cytosine Count

1540672 bp

Genome Length

5433161 bp

Protein-coding Genes

0 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
binding-protein-dependent transport system inner membrane proteinSAMEA3500037_04454Not AvailablePositive4722208 - 472304129859.9
abc transporter permeaseSAMEA3500037_04455Not AvailablePositive4723038 - 472389531727.0
yjcb proteinSAMEA3500037_04456Not AvailableNegative4723942 - 472422310104.8
cyclic diguanylate phosphodiesterase (eal) domain-containing proteinSAMEA3500037_04457Not AvailablePositive4724730 - 472633460377.7
regulatory protein soxsSAMEA3500037_04458Not AvailableNegative4726319 - 472664813116.7
redox-sensitive transcriptional activator soxrSAMEA3500037_04459Not AvailablePositive4726733 - 472719116971.6
glutathione s-transferaseSAMEA3500037_04460Not AvailablePositive4727451 - 472811925136.8
guanine-hypoxanthine permeaseSAMEA3500037_04461Not AvailablePositive4728508 - 472985745666.4
na(+)/h(+) exchanger proteinSAMEA3500037_04462Not AvailablePositive4730005 - 473165160108.9
lysr family regulatory protein cidrSAMEA3500037_04463Not AvailableNegative4731814 - 473269533318.7

Displaying genes 4511 – 4520 of 5146 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total