Klebsiella pneumoniae strain EuSCAPE_FR016

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_FR016 is a Gram-negative, rod-shaped bacterium with a facultative anaerobic metabolism, classified as a chemoheterotroph. This strain is capable of mobility due to the presence of flagella and typically arranges itself in chains, pairs, or as single cells. It thrives optimally at 37°C within a mesophilic temperature range. The strain is associated with a variety of hosts, including Homo sapiens, Gallus gallus, and several other vertebrates and invertebrates, indicating a broad ecological niche. Its pathogenicity is notably significant in humans, where it is linked to various severe health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis, among others. The bacterium's ability to cause a wide range of infections, such as cystitis and intra-abdominal infections, highlights its clinical relevance and potential as a major opportunistic pathogen. Klebsiella pneumoniae strain EuSCAPE_FR016's biotic relationships are characterized as free-living, yet its pathogenic capabilities make it a notable concern in healthcare settings. Its nonsporulating nature suggests that it relies on other survival strategies in adverse conditions. The presence of a single replicon and double membranes further indicates a complex cellular structure typical of Gram-negative bacteria. The versatility of Klebsiella pneumoniae strain EuSCAPE_FR016 in terms of host range and pathogenicity underscores the importance of monitoring and understanding its behavior and resistance mechanisms in both clinical and environmental contexts. This knowledge is crucial for developing effective treatment strategies and managing infections associated with this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_FR016

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_FR016
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_FR016 genome assembly,

Gene Summary

Adenine Count

1158276 bp

Thymine Count

1151426 bp

Guanine Count

1530908 bp

Cytosine Count

1561935 bp

Genome Length

5402545 bp

Protein-coding Genes

4813 genes

Non-Coding Genes

307 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
translation elongation factor gSAMEA3500001_03161Not AvailableNegative3343979 - 334609377547.6
30s ribosomal protein s7SAMEA3500001_03162Not AvailableNegative3346190 - 334666017619.4
30s ribosomal protein s12SAMEA3500001_03163Not AvailableNegative3346757 - 334713113751.9
sulfur transfer complex subunit tusbSAMEA3500001_03164Not AvailableNegative3347256 - 334754310301.4
trna 5-methylaminomethyl-2-thiouridine synthase tuscSAMEA3500001_03165Not AvailableNegative3347551 - 334791013040.6
trna 5-methylaminomethyl-2-thiouridine synthase tusdSAMEA3500001_03166Not AvailableNegative3347910 - 334829613855.4
putative regulatorSAMEA3500001_03167Not AvailableNegative3348296 - 334901826803.1
fkbp-type peptidyl-prolyl cis-trans isomerase fkpaSAMEA3500001_03168Not AvailableNegative3349187 - 335001729492.1
protein slyxSAMEA3500001_03169Not AvailablePositive3350240 - 33504588356.03
fkbp-type peptidyl-prolyl cis-trans isomeraseSAMEA3500001_03170Not AvailableNegative3350517 - 335110420744.9

Displaying genes 3311 – 3320 of 5120 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total