Klebsiella pneumoniae strain EuSCAPE_PL054

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PL054 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe and chemoheterotroph. This organism typically resides in host-associated environments and exhibits various cellular arrangements, including chains, pairs, and singles. It possesses flagella, enabling mobility, and demonstrates mesophilic characteristics, with an optimal growth temperature of 37°C. The strain has a significant pathogenic potential in humans, associated with a wide range of health effects, such as bacteremia, urinary tract infections (UTIs), pneumonia, and various intra-abdominal infections. Furthermore, it is implicated in severe conditions like sepsis, neonatal sepsis, and pyogenic liver abscesses. Its pathogenicity is not limited to humans, as it can infect a diversity of hosts, including domesticated animals such as Gallus gallus (chickens), Sus scrofa (pigs), and Canis lupus familiaris (dogs), as well as various species across the Metazoa and Viridiplantae kingdoms. The presence of Klebsiella pneumoniae strain EuSCAPE_PL054 in multiple hosts indicates its ecological versatility and adaptability. This bacterium's ability to thrive in diverse environments and infect various species underscores its role as a significant pathogen and reflects the importance of monitoring its spread and resistance patterns, particularly in the context of public health and veterinary medicine.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PL054

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PL054
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PL054 genome assembly,

Gene Summary

Adenine Count

1141602 bp

Thymine Count

1142263 bp

Guanine Count

1544163 bp

Cytosine Count

1538215 bp

Genome Length

5366243 bp

Protein-coding Genes

4859 genes

Non-Coding Genes

262 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3499955_04602Not AvailableNegative4878790 - 48790027906.28
Hypothetical proteinSAMEA3499955_04603Not AvailableNegative4878999 - 48792238451.26
Hypothetical proteinSAMEA3499955_04604Not AvailableNegative4879213 - 487992027207.8
Hypothetical proteinSAMEA3499955_04605Not AvailableNegative4879929 - 488050721333.6
Putative serine proteaseSAMEA3499955_04606Not AvailableNegative4880552 - 488137930339.4
uncharacterised proteinSAMEA3499955_04607Not AvailableNegative4881376 - 48815706870.96
Hypothetical proteinSAMEA3499955_04608Not AvailableNegative4881567 - 488199216665.2
Hypothetical proteinSAMEA3499955_04609Not AvailableNegative4881989 - 48822078949.05
Hypothetical proteinSAMEA3499955_04610Not AvailableNegative4882179 - 48824339440.23
Hypothetical proteinSAMEA3499955_04611Not AvailableNegative4882961 - 48831496720.97

Displaying genes 81 – 90 of 5121 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total