Klebsiella pneumoniae strain EuSCAPE_PL037

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PL037 is a Gram-negative, rod-shaped bacterium that is classified as a facultative anaerobe and a chemoheterotroph. It typically exists in various arrangements, including chains, pairs, and singles, and possesses flagella, enabling mobility. This mesophilic organism thrives optimally at 37°C, making it well-suited for growth in mammalian hosts. EuSCAPE_PL037 is predominantly associated with Homo sapiens but has a diverse range of potential hosts, including Gallus gallus (chickens), Danio rerio (zebrafish), and many others, spanning various taxa such as Metazoa, Viridiplantae, and Aves. Its free-living nature allows it to inhabit different environments, but it is also notorious for its pathogenicity, particularly in humans. The strain is implicated in a wide array of health complications, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The presence of this strain in both clinical and environmental contexts underscores its significant role as a human pathogen. The strain's ability to thrive in various hosts and environments may facilitate its transmission and persistence in ecosystems. The diverse health effects associated with Klebsiella pneumoniae, particularly its involvement in severe conditions such as sepsis and neonatal infections, highlight the importance of monitoring and controlling its spread in both healthcare and community settings. Understanding the ecological and biological characteristics of EuSCAPE_PL037 can inform strategies to mitigate its impact on human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PL037

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PL037
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PL037 genome assembly,

Gene Summary

Adenine Count

1190769 bp

Thymine Count

1190122 bp

Guanine Count

1595435 bp

Cytosine Count

1595510 bp

Genome Length

5571836 bp

Protein-coding Genes

5065 genes

Non-Coding Genes

264 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3499994_04973Not AvailableNegative5226216 - 522669817603.1
Hypothetical proteinSAMEA3499994_04974Not AvailableNegative5226879 - 522734317699.2
uncharacterised proteinSAMEA3499994_04975Not AvailableNegative5227658 - 522799313104.3
Putative tail component proteinSAMEA3499994_04976Not AvailableNegative5228077 - 5230974104469.0
uncharacterised proteinSAMEA3499994_04977Not AvailableNegative5231652 - 523200812578.4
uncharacterised proteinSAMEA3499994_04978Not AvailableNegative5232085 - 52322616427.66
Hypothetical proteinSAMEA3499994_04979Not AvailableNegative5232429 - 523291117994.4
Putative major tail proteinSAMEA3499994_04980Not AvailableNegative5232965 - 523413741040.7
Putative tail terminator proteinSAMEA3499994_04981Not AvailableNegative5234161 - 523455313988.7
Hypothetical proteinSAMEA3499994_04982Not AvailableNegative5234550 - 523510120213.0

Displaying genes 161 – 170 of 5329 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1317 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da

Displaying 1–10 of 1317 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total