Klebsiella pneumoniae strain EuSCAPE_PL045

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PL045 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe and a chemoheterotroph. This strain is characterized by its ability to form chains, pairs, and single cells, and possesses flagella, indicating motility. It thrives optimally at 37°C within a mesophilic temperature range and has a single replicon and a double membrane structure. EuSCAPE_PL045 is notably pathogenic to humans and has been associated with a wide array of health issues. These include bacteremia, urinary tract infections, pneumonia, cystitis, intra-abdominal infections, liver abscesses, meningitis, wound infections, and various forms of sepsis. The strain poses a significant risk in clinical settings, contributing to conditions such as neonatal sepsis and catheter-associated urinary tract infections (CAUTI). In terms of its ecological niche, Klebsiella pneumoniae strain EuSCAPE_PL045 is host-associated, with a biotic relationship that allows it to exist freely in diverse environments. It has been identified in various hosts, including Homo sapiens, Gallus gallus, and several other animal species, indicating its adaptability and potential for cross-species transmission. This adaptability may enhance its survival and propagation in different ecological contexts, ultimately impacting public health due to its pathogenic capabilities and resistance potential. Understanding such traits is crucial for developing effective strategies for monitoring and controlling infections caused by this strain.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PL045

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PL045
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PL045 genome assembly,

Gene Summary

Adenine Count

1191718 bp

Thymine Count

1188192 bp

Guanine Count

1589023 bp

Cytosine Count

1598619 bp

Genome Length

5567552 bp

Protein-coding Genes

5046 genes

Non-Coding Genes

279 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Putative tail proteinSAMEA3499937_02036Not AvailableNegative2141851 - 214233618120.9
Tail tape measure proteinSAMEA3499937_02037Not AvailableNegative2142333 - 214496093582.4
Tail assembly proteinSAMEA3499937_02038Not AvailableNegative2145087 - 214538610671.2
Putative major tail tube proteinSAMEA3499937_02039Not AvailableNegative2145439 - 214595418585.2
Tail sheath proteinSAMEA3499937_02040Not AvailableNegative2145964 - 214713642371.2
Tail proteinSAMEA3499937_02041Not AvailableNegative2147275 - 214770315317.6
AttlNot AvailableNot AvailablePositive2414282 - 2414293Not Available
IntegraseSAMEA3499937_02306Not AvailablePositive2415516 - 241674246700.5
uncharacterised proteinSAMEA3499937_02307Not AvailablePositive2416835 - 241777636075.8
Transcriptional regulatorSAMEA3499937_02308Not AvailablePositive2417958 - 241824211198.2

Displaying genes 21 – 30 of 5325 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total