Klebsiella pneumoniae strain EuSCAPE_PL025

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PL025 is a Gram-negative, mesophilic bacterium characterized by its rod shape and the presence of flagella, enabling mobility. It typically exists in chains, pairs, or as single cells. This strain is a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments. It is classified as a chemoheterotroph, relying on organic compounds for energy. EuSCAPE_PL025 is primarily host-associated, with a broad range of potential hosts, including Homo sapiens, various livestock (e.g., Gallus gallus, Sus scrofa, Ovis aries), aquatic species (e.g., Danio rerio), and even plants (Viridiplantae). This versatility suggests a significant ecological role and potential for transmission across different biological kingdoms. Clinically, Klebsiella pneumoniae strain EuSCAPE_PL025 is notable for its pathogenicity in humans, being implicated in various severe health conditions such as bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections. The strain can lead to serious complications, including sepsis and neonatal sepsis, highlighting its impact on public health. Given its ability to inhabit diverse environments and its pathogenic potential, EuSCAPE_PL025 exemplifies the adaptability and resilience of Klebsiella pneumoniae. This adaptability may facilitate the spread of antibiotic resistance genes within and across host species, raising concerns for infectious disease management and control strategies in clinical and ecological contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PL025

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PL025
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PL025 genome assembly,

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

4590 genes

Non-Coding Genes

626 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
threonine efflux proteinSAMEA3499988_04876Not AvailablePositive5150595 - 515091811901.1
inner membrane proteinSAMEA3499988_04877Not AvailablePositive5150911 - 515220348822.3
major facilitator superfamily proteinSAMEA3499988_04878Not AvailablePositive5152257 - 515349845043.3
uncharacterized conserved proteinSAMEA3499988_04879Not AvailablePositive5153524 - 51537639423.06
2-hydroxyglutaryl-coa dehydratase subunit dSAMEA3499988_04880Not AvailablePositive5153861 - 515501242674.3
(r)-2-hydroxyglutaryl-coa dehydratase activatorSAMEA3499988_04881Not AvailablePositive5155022 - 515578926826.3
protein of uncharacterised function (duf3343)SAMEA3499988_04882Not AvailablePositive5155786 - 51560409201.23
permease of the major facilitator superfamilySAMEA3499988_04883Not AvailableNegative5156037 - 515710139485.7
secretion proteinSAMEA3499988_04884Not AvailableNegative5157091 - 515815839600.1
putative marr family regulatory proteinSAMEA3499988_04885Not AvailableNegative5158165 - 515862917508.3

Displaying genes 4951 – 4960 of 5216 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total