Klebsiella pneumoniae strain EuSCAPE_PL005

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PL005 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic lifestyle. Its arrangement in chains, pairs, and singles contributes to its versatility in various environments. This strain is classified as a chemoheterotroph, deriving energy from organic compounds. With an optimal growth temperature of 37°C, EuSCAPE_PL005 is mesophilic, thriving in temperatures typical of mammalian hosts. It possesses flagella, allowing for motility, which can enhance its ability to colonize and infect various hosts. The strain has a unique biotic relationship as a free-living organism, yet it is associated with numerous hosts, including Homo sapiens, Gallus gallus, and various other Metazoa and Viridiplantae. Klebsiella pneumoniae strain EuSCAPE_PL005 is notable for its pathogenicity in humans, causing a range of serious health conditions, including bacteremia, urinary tract infections, pneumonia, and sepsis. The ability to infect both humans and a diverse array of animal species underscores its ecological adaptability and potential for zoonotic transmission. This strain, characterized by nonsporulating behavior and a single replicon within its two membranes, exemplifies the complex interactions between pathogenic bacteria and their hosts. Understanding its pathogenic profile and ecological relationships is essential for managing infections and developing strategies to mitigate the impact of Klebsiella pneumoniae in both human and veterinary medicine.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PL005

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PL005
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PL005 genome assembly,

Gene Summary

Adenine Count

1175344 bp

Thymine Count

1168287 bp

Guanine Count

1571961 bp

Cytosine Count

1582523 bp

Genome Length

5498115 bp

Protein-coding Genes

4966 genes

Non-Coding Genes

201 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Tail proteinSAMEA3499935_01133Not AvailablePositive1167144 - 11673477431.76
HolinSAMEA3499935_01134Not AvailablePositive1167351 - 11675668077.99
LysozymeSAMEA3499935_01135Not AvailablePositive1167547 - 116805618464.4
Lysb family lysis regulatory proteinSAMEA3499935_01136Not AvailablePositive1168061 - 116848915933.2
Tail proteinSAMEA3499935_01137Not AvailablePositive1168585 - 116901615912.8
Virion morphogenesis proteinSAMEA3499935_01138Not AvailablePositive1169009 - 116946117610.3
uncharacterised proteinSAMEA3499935_01139Not AvailableNegative1169474 - 117013625164.9
Baseplate assembly protein vSAMEA3499935_01140Not AvailablePositive1170240 - 117081220583.1
Baseplate assembly proteinSAMEA3499935_01141Not AvailablePositive1170809 - 117117113230.9
Baseplate assembly protein jSAMEA3499935_01142Not AvailablePositive1171158 - 117206632606.6

Displaying genes 21 – 30 of 5167 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total