Klebsiella pneumoniae strain EuSCAPE_PL007

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_PL007 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. This strain is characterized by its capacity to form chains, pairs, and singles, indicating a versatile cell arrangement. It possesses flagella, which contribute to its mobility, and has an optimal growth temperature of 37°C, classifying it as mesophilic. The ecological niche of EuSCAPE_PL007 is predominantly host-associated, with a diverse range of hosts including Homo sapiens, Gallus gallus, and various other vertebrates such as Metazoa, Danio rerio, and Sus scrofa. This wide host range suggests its adaptability and potential for transmission across different species. Clinically, Klebsiella pneumoniae is associated with a variety of health issues, including but not limited to bacteremia, urinary tract infections, pneumonia, and intra-abdominal infections. Its pathogenicity is notably significant in humans, where it can lead to severe conditions such as sepsis and neonatal infections. The strain does not exhibit sporulation, which may influence its survival strategies and interactions within host environments. The presence of multiple health complications linked to this bacterium underscores its role as a significant opportunistic pathogen, particularly in immunocompromised individuals. Understanding the ecological dynamics and pathogenic mechanisms of Klebsiella pneumoniae strain EuSCAPE_PL007 is critical for developing effective treatment strategies and managing its impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_PL007

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_PL007
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_PL007 genome assembly,

Gene Summary

Adenine Count

1182438 bp

Thymine Count

1178420 bp

Guanine Count

1579557 bp

Cytosine Count

1589962 bp

Genome Length

5530377 bp

Protein-coding Genes

5045 genes

Non-Coding Genes

220 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
efflux (pet) family inner membrane protein yccsSAMEA3499938_00176Not AvailablePositive174301 - 17643680293.8
competence activator protein sxySAMEA3499938_00177Not AvailableNegative176450 - 17704622577.5
cell division inhibitorSAMEA3499938_00178Not AvailablePositive177395 - 17790418929.8
outer membrane protein aSAMEA3499938_00179Not AvailablePositive178257 - 17932738046.6
dehydrogenaseSAMEA3499938_00180Not AvailableNegative179459 - 17991117710.4
atp-dependent protease laSAMEA3499938_00181Not AvailablePositive180097 - 18185465099.7
3-hydroxydecanoyl-(acyl carrier protein) dehydrataseSAMEA3499938_00182Not AvailablePositive181924 - 18244219085.3
lipoproteinSAMEA3499938_00183Not AvailableNegative182932 - 18349520386.2
paraquat-inducible protein bSAMEA3499938_00184Not AvailableNegative183495 - 18513260150.3
paraquat-inducible membrane protein aSAMEA3499938_00185Not AvailableNegative185122 - 18639047157.2

Displaying genes 341 – 350 of 5265 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total