Klebsiella pneumoniae strain EuSCAPE_EE013

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_EE013 is a Gram-negative, rod-shaped bacterium known for its pathogenicity in humans and various hosts, including mammals, birds, and plants. It is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments, and is a chemoheterotroph, obtaining energy through organic compounds. This strain exhibits a range of cellular arrangements, including chains, pairs, and singles, and possesses flagella, enabling mobility. Its optimal growth temperature is 37°C, placing it within the mesophilic temperature range. The bacterium has a single replicon and two membranes, characteristic of Gram-negative bacteria. Klebsiella pneumoniae strain EuSCAPE_EE013 is associated with numerous health complications, particularly in humans. It is known to cause a variety of infections such as bacteremia, urinary tract infections, pneumonia, cystitis, intra-abdominal infections, liver abscesses, and meningitis. Other documented health effects include wound infections, bloodstream infections, neonatal sepsis, and pulmonary infections, highlighting its clinical significance. The strain's diverse host range and ability to cause severe infections underscore its ecological versatility and capacity to impact health across different species. As a free-living organism associated with various hosts, Klebsiella pneumoniae strain EuSCAPE_EE013 plays a notable role in the microbial landscape, affecting not only human health but also the health of domestic and wild animals. This multifaceted interaction illustrates the importance of monitoring such pathogens in both clinical and environmental contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_EE013

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_EE013
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_EE013 genome assembly,

Gene Summary

Adenine Count

1164384 bp

Thymine Count

1167486 bp

Guanine Count

1557652 bp

Cytosine Count

1566180 bp

Genome Length

5455702 bp

Protein-coding Genes

4899 genes

Non-Coding Genes

350 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
integrating conjugative element protein, pfl_4709 familySAMEA3499917_00470Not AvailablePositive482844 - 48323914586.5
integrating conjugative element protein, pfl_4710 familySAMEA3499917_00471Not AvailablePositive483236 - 48417734120.5
integrating conjugative element protein, pfl_4711 familySAMEA3499917_00472Not AvailablePositive484193 - 48561450098.2
uncharacterised proteinSAMEA3499917_00473Not AvailablePositive485611 - 48595212716.1
trag-like protein, n-terminal regionSAMEA3499917_00474Not AvailablePositive485955 - 48748455768.1
uncharacterised proteinSAMEA3499917_00475Not AvailableNegative487528 - 48782710826.7
transcriptional regulator nlpSAMEA3499917_00476Not AvailableNegative488052 - 4883039076.94
xre family transcriptional regulatorSAMEA3499917_00477Not AvailablePositive488407 - 4886529137.43
cold shock proteinSAMEA3499917_00478Not AvailableNegative488731 - 48918616393.9
uncharacterised proteinSAMEA3499917_00479Not AvailablePositive489198 - 4893686224.79

Displaying genes 771 – 780 of 5249 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total