Klebsiella pneumoniae strain EuSCAPE_EE015

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_EE015 is a gram-negative, rod-shaped bacterium notable for its pathogenic potential in humans and various animal hosts. This strain demonstrates a facultative anaerobic metabolism, utilizing organic compounds as a chemoheterotroph. It typically exists in chains, pairs, or as single cells, and possesses flagella, indicating mobility. The optimal growth temperature for this strain is 37°C, placing it within the mesophilic range. K. pneumoniae EuSCAPE_EE015 is associated with numerous health issues, particularly in humans, where it can cause conditions such as bacteremia, pneumonia, urinary tract infections, and a variety of intra-abdominal infections. It is also implicated in severe health conditions like sepsis and neonatal sepsis. In addition to humans, this strain can infect a diverse range of hosts, including domesticated animals such as Gallus gallus (chickens), Sus scrofa (pigs), and Canis lupus familiaris (dogs), as well as aquatic species like Danio rerio (zebrafish) and various plants. The biotic relationship of K. pneumoniae EuSCAPE_EE015 is categorized as free-living, highlighting its adaptability in different environments. The presence of a single replicon and double membranes suggests a typical gram-negative bacterial structure, which is important for its resilience in various ecological niches. The strain's ability to thrive in diverse hosts underscores its ecological versatility and potential role in both environmental and clinical microbiomes, illustrating the complex interactions between pathogenic bacteria and their hosts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_EE015

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_EE015
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_EE015 genome assembly,

Gene Summary

Adenine Count

1180403 bp

Thymine Count

1170909 bp

Guanine Count

1543249 bp

Cytosine Count

1602789 bp

Genome Length

5497350 bp

Protein-coding Genes

4921 genes

Non-Coding Genes

258 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Aipr proteinSAMEA3499919_00287Not AvailableNegative322815 - 32455764687.4
Hypothetical proteinSAMEA3499919_00288Not AvailableNegative324833 - 32551023858.2
Dna damage inducible proteinSAMEA3499919_00289Not AvailableNegative325625 - 3258589160.16
Hypothetical proteinSAMEA3499919_00290Not AvailableNegative325869 - 3260577286.72
Replication endonucleaseSAMEA3499919_00291Not AvailableNegative326211 - 32862592543.6
Dna adenine methyltransferaseSAMEA3499919_00292Not AvailableNegative328622 - 32947932115.9
Zinc-finger containing proteinSAMEA3499919_00293Not AvailableNegative329476 - 3297038307.18
Hypothetical proteinSAMEA3499919_00294Not AvailableNegative329703 - 3299368581.26
Hypothetical proteinSAMEA3499919_00295Not AvailableNegative330004 - 33034512839.7
Hypothetical proteinSAMEA3499919_00296Not AvailableNegative330309 - 3305097717.47

Displaying genes 31 – 40 of 5179 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total