Klebsiella pneumoniae strain EuSCAPE_EE012

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_EE012 is a Gram-negative, rod-shaped bacterium that thrives in host-associated environments. As a facultative anaerobe and chemoheterotroph, it can metabolize organic compounds for energy, allowing it to adapt to varying oxygen levels. The organism typically forms chains, pairs, or exists as singles, and it possesses flagella, indicating motility. This strain is mesophilic, with an optimal growth temperature of 37°C, which aligns with the body temperature of its primary host, Homo sapiens. It exhibits a complex biotic relationship, being free-living yet capable of acting as a significant pathogen in various hosts, including mammals like Canis lupus familiaris and poultry such as Gallus gallus. Klebsiella pneumoniae strain EuSCAPE_EE012 is associated with numerous health effects, particularly in humans, where it can cause conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis. Other notable infections include intra-abdominal infections and liver abscesses, highlighting its pathogenic potential. The strain's ability to cause a wide range of diseases underscores its importance in clinical microbiology and public health. Understanding the ecological and biological roles of Klebsiella pneumoniae, particularly strain EuSCAPE_EE012, is crucial for managing its pathogenic impacts. The strain's presence in diverse hosts and environments illustrates its adaptability and potential for transmission, emphasizing the need for vigilance regarding its role in infectious diseases.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_EE012

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_EE012
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_EE012 genome assembly,

Gene Summary

Adenine Count

1150316 bp

Thymine Count

1146394 bp

Guanine Count

1533042 bp

Cytosine Count

1567400 bp

Genome Length

5397152 bp

Protein-coding Genes

4909 genes

Non-Coding Genes

147 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
putative enzymeSAMEA3499916_01485Not AvailableNegative1583336 - 158473352764.8
phage shock protein dSAMEA3499916_01486Not AvailableNegative1584836 - 15850547807.01
phage shock protein cSAMEA3499916_01487Not AvailableNegative1585083 - 158544213350.6
phage shock protein bSAMEA3499916_01488Not AvailableNegative1585442 - 15856668761.7
phage shock protein pspaSAMEA3499916_01489Not AvailableNegative1585722 - 158639025445.2
psp operon transcriptional activatorSAMEA3499916_01490Not AvailablePositive1586543 - 158753237017.7
transporterSAMEA3499916_01491Not AvailableNegative1587523 - 158891448364.5
amidohydrolase family proteinSAMEA3499916_01492Not AvailableNegative1588940 - 159010942503.8
arac family transcriptional regulatorSAMEA3499916_01493Not AvailablePositive1590281 - 159259088323.3
transcriptional regulatorSAMEA3499916_01494Not AvailableNegative1592569 - 159339931202.2

Displaying genes 1551 – 1560 of 5056 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total