Klebsiella pneumoniae strain EuSCAPE_AT024

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_AT024 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is capable of mobility and possesses flagella, which may contribute to its ability to colonize various hosts. The strain typically forms in chains, pairs, or as single cells and is mesophilic, thriving optimally at 37°C. K. pneumoniae strain EuSCAPE_AT024 is primarily associated with a range of hosts, including Homo sapiens (humans), Gallus gallus (chickens), and several other vertebrates such as fish, mammals, and amphibians. This diverse host range underscores its ecological adaptability. Importantly, this bacterium is known for its pathogenic potential in humans, being linked to numerous health effects, including bacteremia, urinary tract infections, pneumonia, and sepsis, among other serious conditions. With only one replicon and a biotic relationship categorized as free-living, K. pneumoniae strain EuSCAPE_AT024 can survive independently while also posing significant health risks to its hosts. The pathogenicity of this strain highlights its importance in both clinical and ecological contexts, suggesting that its presence is not merely a byproduct of human activity but a significant player in host-associated microbiomes. Understanding the traits and behaviors of K. pneumoniae strain EuSCAPE_AT024 can provide insights into its role within various ecosystems and its impact on human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_AT024

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_AT024
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_AT024 genome assembly,

Gene Summary

Adenine Count

1113268 bp

Thymine Count

1108980 bp

Guanine Count

1496451 bp

Cytosine Count

1511650 bp

Genome Length

5230349 bp

Protein-coding Genes

4763 genes

Non-Coding Genes

196 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
uncharacterised proteinSAMEA3499896_01938Not AvailablePositive2071330 - 207274854238.4
Cp4-57 prophageSAMEA3499896_01939Not AvailableNegative2072760 - 207395944797.4
Tmrna,resume;Not AvailableNot AvailablePositive2074144 - 2074506Not Available
Ssra-binding proteinSAMEA3499896_01941Not AvailableNegative2074651 - 207513318240.1
Type ii toxin-antitoxin system toxin rataSAMEA3499896_01942Not AvailablePositive2075283 - 207572016039.5
Rnfh family proteinSAMEA3499896_01943Not AvailablePositive2075710 - 207600010821.0
Outer membrane protein assembly factor bameSAMEA3499896_01944Not AvailableNegative2076067 - 207640812414.0
Dna repair protein recnSAMEA3499896_01945Not AvailableNegative2076556 - 207821761373.2
Dna repair protein recnSAMEA3499896_01946Not AvailableNegative2078304 - 207918232394.1
Heat shock proteinSAMEA3499896_01947Not AvailablePositive2079307 - 207989721751.9

Displaying genes 61 – 70 of 4959 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total