Klebsiella pneumoniae strain EuSCAPE_AT023

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_AT023 is a significant pathogen characterized primarily by its negative Gram stain and rod shape. This strain is a chemoheterotroph, deriving energy from organic compounds, and is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It typically exists in chains, pairs, or as single cells, and possesses flagella, which contribute to its mobility. The strain is mesophilic, with an optimal growth temperature of 37°C, making it well-suited to the human body, where it is commonly found as a host-associated organism. Its biotic relationship is classified as free-living, indicating that it can survive independently while still being capable of causing a range of health issues in various hosts, including humans and several animal species such as Gallus gallus (chickens), Danio rerio (zebrafish), and Canis lupus familiaris (domestic dogs). Klebsiella pneumoniae strain EuSCAPE_AT023 is linked to numerous health complications, including bacteremia, urinary tract infections, pneumonia, and a range of intra-abdominal infections. Its pathogenicity is particularly concerning in human health, as it is responsible for severe conditions such as sepsis and neonatal sepsis. The strain's diverse host range highlights its ecological adaptability and potential for zoonotic transmission, emphasizing the need for ongoing surveillance and research to understand its impact on both human and animal health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_AT023

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_AT023
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_AT023 genome assembly,

Gene Summary

Adenine Count

1206998 bp

Thymine Count

1209208 bp

Guanine Count

1608446 bp

Cytosine Count

1617417 bp

Genome Length

5642069 bp

Protein-coding Genes

5161 genes

Non-Coding Genes

243 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Major tail tube proteinSAMEA3499895_00349Not AvailablePositive355914 - 35642918846.4
Phage tail assembly proteinSAMEA3499895_00350Not AvailablePositive356484 - 35678610869.5
Tail tape measure proteinSAMEA3499895_00351Not AvailablePositive356913 - 359990108901.0
Tail proteinSAMEA3499895_00352Not AvailablePositive359987 - 36047218060.9
Tail proteinSAMEA3499895_00353Not AvailablePositive360469 - 36156941000.7
Hypothetical proteinSAMEA3499895_00354Not AvailablePositive361660 - 3618787964.55
AttrNot AvailableNot AvailablePositive361951 - 361969Not Available
Protein of unknown function duf927SAMEA3499895_01726Not AvailablePositive1821658 - 182379377917.0
uncharacterised proteinSAMEA3499895_01727Not AvailablePositive1824136 - 182447112245.2
uncharacterised proteinSAMEA3499895_01728Not AvailableNegative1824520 - 182503218229.7

Displaying genes 41 – 50 of 5404 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total