Klebsiella pneumoniae strain EuSCAPE_AT023

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_AT023 is a significant pathogen characterized primarily by its negative Gram stain and rod shape. This strain is a chemoheterotroph, deriving energy from organic compounds, and is classified as a facultative anaerobe, allowing it to thrive in both aerobic and anaerobic environments. It typically exists in chains, pairs, or as single cells, and possesses flagella, which contribute to its mobility. The strain is mesophilic, with an optimal growth temperature of 37°C, making it well-suited to the human body, where it is commonly found as a host-associated organism. Its biotic relationship is classified as free-living, indicating that it can survive independently while still being capable of causing a range of health issues in various hosts, including humans and several animal species such as Gallus gallus (chickens), Danio rerio (zebrafish), and Canis lupus familiaris (domestic dogs). Klebsiella pneumoniae strain EuSCAPE_AT023 is linked to numerous health complications, including bacteremia, urinary tract infections, pneumonia, and a range of intra-abdominal infections. Its pathogenicity is particularly concerning in human health, as it is responsible for severe conditions such as sepsis and neonatal sepsis. The strain's diverse host range highlights its ecological adaptability and potential for zoonotic transmission, emphasizing the need for ongoing surveillance and research to understand its impact on both human and animal health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_AT023

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_AT023
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_AT023 genome assembly,

Gene Summary

Adenine Count

1206998 bp

Thymine Count

1209208 bp

Guanine Count

1608446 bp

Cytosine Count

1617417 bp

Genome Length

5642069 bp

Protein-coding Genes

5161 genes

Non-Coding Genes

243 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
f0f1 atp synthase subunit deltaSAMEA3499895_04462Not AvailableNegative4730695 - 473122819531.6
atp synthase subunit bSAMEA3499895_04463Not AvailableNegative4731243 - 473171317376.0
atp synthase subunit cSAMEA3499895_04464Not AvailableNegative4731764 - 47320038256.71
atp synthase subunit aSAMEA3499895_04465Not AvailableNegative4732053 - 473286830487.3
f0f1 atp synthase subunit iSAMEA3499895_04466Not AvailableNegative4732876 - 473325613670.6
rrna small subunit methyltransferaseSAMEA3499895_04467Not AvailableNegative4733873 - 473449623133.1
trna uridine 5-carboxymethylaminomethyl modification protein gidaSAMEA3499895_04468Not AvailableNegative4734612 - 473650170103.9
flavodoxinSAMEA3499895_04469Not AvailableNegative4736883 - 473732315709.5
regulatory protein asncSAMEA3499895_04470Not AvailableNegative4737423 - 473788116938.7
asparagine synthetase asnaSAMEA3499895_04471Not AvailablePositive4738033 - 473902536814.0

Displaying genes 4531 – 4540 of 5404 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total