Klebsiella pneumoniae strain EuSCAPE_TR253

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR253 is a Gram-negative, rod-shaped bacterium classified as a facultative anaerobe, thriving optimally at 37°C within the mesophilic temperature range. This strain exhibits mobility due to the presence of flagella and typically arranges itself in chains, pairs, or as single cells. It is a chemoheterotroph, utilizing organic compounds as an energy source, and it possesses a biotic relationship characterized as free-living. The strain has been identified in various hosts, including Homo sapiens, Gallus gallus, and multiple other Metazoa, indicating its broad ecological presence. Notably, K. pneumoniae EuSCAPE_TR253 is associated with a range of health effects in humans, such as bacteremia, urinary tract infections, pneumonia, and various other serious infections including meningitis and sepsis. This highlights its pathogenic potential in human health. K. pneumoniae strains are known for their ability to cause severe infections, particularly in immunocompromised individuals, and they pose significant challenges in clinical settings. The strain's capacity to thrive in diverse environments and its association with numerous hosts underline its adaptability and potential for zoonotic transmission. This adaptability, coupled with its pathogenicity, emphasizes the importance of monitoring Klebsiella pneumoniae populations in both human and animal health contexts, as they can contribute to the emergence and spread of antibiotic-resistant infections.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR253

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR253
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR253 genome assembly,

Gene Summary

Adenine Count

1194544 bp

Thymine Count

1192074 bp

Guanine Count

1587637 bp

Cytosine Count

1589190 bp

Genome Length

5563445 bp

Protein-coding Genes

5156 genes

Non-Coding Genes

90 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ding family atp-dependent helicase yoaaSAMEA3729853_00055Not AvailableNegative61925 - 6383570160.8
endoribonuclease l-pspSAMEA3729853_00056Not AvailablePositive63967 - 6431112553.9
uncharacterized protein conserved in bacteriaSAMEA3729853_00057Not AvailableNegative64312 - 644976748.82
para-aminobenzoate synthase component iSAMEA3729853_00058Not AvailablePositive64586 - 6594150384.8
nudix hydrolase yeabSAMEA3729853_00059Not AvailablePositive65945 - 6652321328.8
l-serine dehydrataseSAMEA3729853_00060Not AvailablePositive66686 - 6805048999.0
rtn proteinSAMEA3729853_00061Not AvailablePositive68233 - 6981058173.4
magnesium and cobalt efflux protein corcSAMEA3729853_00062Not AvailableNegative69844 - 7140356457.5
pts system mannose-specific transporter subunit iiaSAMEA3729853_00063Not AvailablePositive71850 - 7282134895.4
pts system proteinSAMEA3729853_00064Not AvailablePositive72878 - 7367827575.5

Displaying genes 61 – 70 of 5246 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total