Klebsiella pneumoniae strain EuSCAPE_TR239

Klebsiella pneumoniae strain EuSCAPE_TR239 is a Gram-negative, rod-shaped bacterium known for its pathogenic potential in humans. It is classified as a facultative anaerobe, capable of thriving in both oxygen-rich and low-oxygen environments, with an optimal growth temperature of 37°C, typical of mesophilic organisms. This strain is motile and possesses flagella, which may contribute to its ability to colonize various hosts. K. pneumoniae EuSCAPE_TR239 is primarily associated with human infections, leading to severe health issues such as bacteremia, urinary tract infections, pneumonia, and sepsis. In addition to humans, it has been identified in a wide array of hosts, including Gallus gallus (chickens), various Metazoa, and even some plants, indicating its ecological versatility. The bacterium demonstrates a free-living biotic relationship, suggesting its capability to exist independently in diverse environments. Notably, this strain does not form spores and contains a single replicon within its cellular structure, surrounded by two membranes. The health effects associated with K. pneumoniae EuSCAPE_TR239 highlight its significance in clinical settings, especially due to its role in serious infections like neonatal sepsis and pyogenic liver abscesses. The presence of K. pneumoniae in multiple host species underlines its ecological adaptability and potential for cross-species transmission. This adaptability, coupled with its pathogenicity, poses challenges for public health, necessitating ongoing monitoring and research to understand its behavior in various environments and its impact on both human and animal health.