Klebsiella pneumoniae strain EuSCAPE_TR237

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR237 is a facultative anaerobic, gram-negative bacterium characterized by its rod shape and mobility, facilitated by flagella. This strain is part of the Chemoheterotroph metabolic group, indicating it derives energy from organic compounds. It typically grows optimally at 37°C and is classified as mesophilic, thriving within moderate temperature ranges. This strain exhibits a diverse biotic relationship, being free-living and associated with numerous hosts, including Homo sapiens, various species of birds (Phasianidae, Gallus gallus), mammals (Canis lupus familiaris, Sus scrofa, Equidae), and even some plants (Viridiplantae). Such a wide host range highlights its ecological versatility and adaptability. Klebsiella pneumoniae is known for its significant health impacts on humans, causing a variety of infections such as bacteremia, urinary tract infections (UTIs), pneumonia, and intra-abdominal infections. Other serious health issues linked to this bacterium include liver abscesses, meningitis, and sepsis, which underline its pathogenicity in humans. The strain's ability to cause multiple types of infections, including those affecting neonates, emphasizes its clinical relevance and the importance of monitoring its prevalence in healthcare settings. Given its capacity to thrive in diverse environments and its association with numerous infections, the ecological and public health implications of Klebsiella pneumoniae strain EuSCAPE_TR237 are considerable. Understanding its behaviors and interactions in various hosts can help inform strategies for infection control and management in both human and veterinary contexts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR237

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR237
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR237 genome assembly,

Gene Summary

Adenine Count

1215070 bp

Thymine Count

1216074 bp

Guanine Count

1603278 bp

Cytosine Count

1630019 bp

Genome Length

5664441 bp

Protein-coding Genes

5080 genes

Non-Coding Genes

298 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Trna-serNot AvailableNot AvailablePositive2962812 - 2962899Not Available
putative cysteine hydrolaseSAMEA3729839_02828Not AvailableNegative2963045 - 296372224095.9
putative cytoplasmic proteinSAMEA3729839_02829Not AvailableNegative2963741 - 296460130679.3
transcriptional regulatorSAMEA3729839_02830Not AvailablePositive2964716 - 296562133692.9
tetr family transcriptional regulatorSAMEA3729839_02831Not AvailableNegative2965811 - 296625716901.4
putative arginase/agmatinase/formimionoglutamate hydrolaseSAMEA3729839_02832Not AvailableNegative2966478 - 296734131331.1
Trna-serNot AvailableNot AvailablePositive2968105 - 2968192Not Available
2-hydroxyacid dehydrogenase ycdwSAMEA3729839_02834Not AvailablePositive2968461 - 296939935171.4
hydrolase ycdxSAMEA3729839_02835Not AvailablePositive2969488 - 297022526943.2
chaperone, tord familySAMEA3729839_02836Not AvailablePositive2970248 - 297080220597.3

Displaying genes 2861 – 2870 of 5378 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total