Klebsiella pneumoniae strain EuSCAPE_TR231

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR231 is a Gram-negative, rod-shaped bacterium and a facultative anaerobe, thriving optimally at 37°C within a mesophilic temperature range. This strain exhibits motility, possessing flagella, and typically arranges itself in chains, pairs, or single cells. As a chemoheterotroph, it derives energy from organic compounds and is associated with various hosts, including Homo sapiens, Gallus gallus, and multiple other species such as Danio rerio and Canis lupus familiaris. This strain is recognized for its pathogenic potential in humans, being linked to numerous health complications. It can cause bacteremia, pneumonia, urinary tract infections, and various intra-abdominal infections. Other serious conditions attributed to K. pneumoniae EuSCAPE_TR231 include liver abscesses, sepsis, and neonatal sepsis, highlighting its significant role in clinical settings, particularly in immunocompromised patients. Despite its pathogenic traits, K. pneumoniae EuSCAPE_TR231 is also noted for its biotic relationship as a free-living organism. The presence of a single replicon and two membranes suggests a typical Gram-negative bacterial structure, which may contribute to its adaptability and survival in diverse environments. The ability of this strain to affect a wide range of hosts indicates an ecological versatility that may facilitate its transmission and persistence in various ecosystems, from human health contexts to animal reservoirs. This adaptability underscores the importance of monitoring K. pneumoniae strains in both clinical and environmental settings, given their potential impact on public health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR231

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR231
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR231 genome assembly,

Gene Summary

Adenine Count

1199536 bp

Thymine Count

1198617 bp

Guanine Count

1604085 bp

Cytosine Count

1604765 bp

Genome Length

5607003 bp

Protein-coding Genes

5040 genes

Non-Coding Genes

200 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Major capsid head protein precursorSAMEA3729828_00047Not AvailablePositive47519 - 4880546094.1
Trna-pro;Not AvailableNot AvailablePositive47746 - 47822Not Available
Trna-ser;Not AvailableNot AvailablePositive47865 - 47951Not Available
Trna-his;Not AvailableNot AvailablePositive47975 - 48050Not Available
Trna-arg;Not AvailableNot AvailablePositive48106 - 48182Not Available
Gp7SAMEA3729828_00048Not AvailablePositive48864 - 491249505.03
Head-tail connector proteinSAMEA3729828_00049Not AvailablePositive49105 - 4942212149.5
Gp9SAMEA3729828_00050Not AvailablePositive49419 - 4975712571.1
Gp10SAMEA3729828_00051Not AvailablePositive49738 - 5012714743.9
Gp11SAMEA3729828_00052Not AvailablePositive50124 - 5052514904.2

Displaying genes 31 – 40 of 5240 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total