Klebsiella pneumoniae strain EuSCAPE_TR208

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR208 is a Gram-negative, rod-shaped bacterium that displays mobility due to the presence of flagella. This strain is classified as a facultative anaerobe and is capable of utilizing a chemoheterotrophic energy source. Its optimal growth temperature is 37°C, placing it in the mesophilic temperature range. The organism typically exists in various arrangements, including chains, pairs, and singles, and features a cell structure with two membranes and a single replicon. EuSCAPE_TR208 is known for its pathogenic effects on a variety of hosts, including Homo sapiens, Gallus gallus, and other Metazoa, leading to numerous health issues. In humans, it is associated with serious conditions such as bacteremia, urinary tract infections, pneumonia, and sepsis, among others. This wide host range indicates its adaptability and potential for cross-species transmission. As a free-living organism, Klebsiella pneumoniae strain EuSCAPE_TR208 plays a significant role in the microbiome of various environments where it may be found. Its ability to cause disease in multiple hosts highlights its ecological versatility and significance in public health. The strain's association with antibiotic resistance and its presence in clinical settings emphasizes the importance of monitoring its spread and understanding its pathogenic mechanisms to mitigate its impact on human health.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR208

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR208
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR208 genome assembly,

Gene Summary

Adenine Count

1217388 bp

Thymine Count

1217659 bp

Guanine Count

1609446 bp

Cytosine Count

1612037 bp

Genome Length

5656530 bp

Protein-coding Genes

5134 genes

Non-Coding Genes

243 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Terminase small subunitSAMEA3729790_02772Not AvailableNegative2903752 - 290475637544.0
Hypothetical proteinSAMEA3729790_02773Not AvailableNegative2905619 - 29058649005.58
Hypothetical proteinSAMEA3729790_02774Not AvailableNegative2906823 - 29070989669.44
HolinSAMEA3729790_02775Not AvailableNegative2907095 - 290743912500.9
Soluble endolysin proteinSAMEA3729790_02776Not AvailableNegative2907436 - 290797519797.6
Holin proteinSAMEA3729790_02777Not AvailableNegative2907972 - 290828311063.8
Hypothetical proteinSAMEA3729790_02778Not AvailableNegative2909236 - 29094939645.26
Trna,type:thr,anti_codon:tgt;Not AvailableNot AvailablePositive2909561 - 2909636Not Available
Late gene regulator qSAMEA3729790_02780Not AvailableNegative2909828 - 291064930166.3
uncharacterised proteinSAMEA3729790_02781Not AvailableNegative2910646 - 29107684546.57

Displaying genes 121 – 130 of 5377 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total