Klebsiella pneumoniae strain EuSCAPE_TR202

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR202 is a Gram-negative, rod-shaped bacterium that exhibits a versatile lifestyle as a facultative anaerobe, capable of thriving in both aerobic and anaerobic environments. This strain is chemoheterotrophic, utilizing organic compounds as energy sources, and it typically resides in host-associated habitats, including various hosts such as Homo sapiens, Gallus gallus, and other metazoans. EuSCAPE_TR202 is characterized by its mobility, enabled by the presence of flagella, and it typically appears in chains, pairs, or as single cells. With a mesophilic temperature range, it grows optimally at 37 degrees Celsius, aligning with human body temperature, which is significant for its pathogenicity in humans. This strain is notably pathogenic, associated with a wide array of health effects including bacteremia, urinary tract infections, pneumonia, and sepsis. It is implicated in serious conditions such as intra-abdominal infections, liver abscesses, and neonatal sepsis, highlighting its clinical relevance. Klebsiella pneumoniae strain EuSCAPE_TR202 is nonsporulating and possesses a dual-membrane structure typical of Gram-negative bacteria. Its capability to establish infections across various hosts underscores its ecological adaptability and the potential for zoonotic transmission, which poses challenges for public health. The broad spectrum of diseases linked to this strain emphasizes the importance of monitoring and understanding its epidemiology in both human and animal populations.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR202

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR202
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR202 genome assembly,

Gene Summary

Adenine Count

1215976 bp

Thymine Count

1205818 bp

Guanine Count

1585641 bp

Cytosine Count

1626589 bp

Genome Length

5634024 bp

Protein-coding Genes

5101 genes

Non-Coding Genes

300 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
auxin efflux carrierSAMEA3729778_01515Not AvailablePositive1560169 - 156112833332.4
phosphoribosyl-dephospho-coa transferaseSAMEA3729778_01516Not AvailablePositive1561132 - 156174922952.5
malonyl coa-acyl carrier protein transacylaseSAMEA3729778_01517Not AvailablePositive1561749 - 156265132127.1
malonate utilization transcriptional regulatorSAMEA3729778_01518Not AvailableNegative1562641 - 156356734652.3
malate:quinone oxidoreductaseSAMEA3729778_01519Not AvailableNegative1563725 - 156537159972.4
glucokinase regulatory proteinSAMEA3729778_01520Not AvailableNegative1565645 - 156656532755.2
uncharacterised proteinSAMEA3729778_01521Not AvailableNegative1566729 - 156708513954.2
sensory histidine kinase dcusSAMEA3729778_01522Not AvailablePositive1567241 - 156885758938.6
fumarate respiration transcriptional regulator dcurSAMEA3729778_01523Not AvailablePositive1568854 - 156957326994.4
apbe family proteinSAMEA3729778_01524Not AvailableNegative1569554 - 157050434958.1

Displaying genes 1701 – 1710 of 5401 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total