Klebsiella pneumoniae strain EuSCAPE_TR197

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR197 is a Gram-negative, rod-shaped bacterium that is classified as a chemoheterotroph and a facultative anaerobe. This strain can be found in various habitats associated with hosts, including Homo sapiens and several other organisms such as Gallus gallus, Canis lupus familiaris, and Sus scrofa, among others. The bacterium typically arranges itself in chains, pairs, or singles, and possesses flagella, allowing for mobility. EuSCAPE_TR197 is mesophilic, with an optimal growth temperature of 37°C, making it well-suited for survival within the human body, where it can cause a wide range of health issues. These include bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections, among others. The pathogenicity of this strain primarily affects humans but also has implications for other species, indicating a broader ecological impact. Notably, Klebsiella pneumoniae strain EuSCAPE_TR197 is nonsporulating and has a single replicon with two membranes. Its ability to thrive in diverse environments and cause significant health issues underscores its role as an opportunistic pathogen in both clinical and ecological contexts. The presence of this strain in various hosts highlights the interconnectedness of microbial populations and their potential effects on different organisms, particularly in terms of health and disease dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR197

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR197
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR197 genome assembly,

Gene Summary

Adenine Count

1151655 bp

Thymine Count

1149002 bp

Guanine Count

1525981 bp

Cytosine Count

1555876 bp

Genome Length

5382514 bp

Protein-coding Genes

4891 genes

Non-Coding Genes

176 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
membrane proteinSAMEA3729771_00183Not AvailablePositive198950 - 19972928256.5
chromosome partition protein mukfSAMEA3729771_00184Not AvailableNegative199706 - 20059934424.5
3-deoxy-manno-octulosonate cytidylyltransferaseSAMEA3729771_00185Not AvailableNegative200736 - 20148227335.7
protein ycar in kdo2-lipid a biosynthesis clusterSAMEA3729771_00186Not AvailableNegative201479 - 2016616797.27
uncharacterized protein conserved in bacteriaSAMEA3729771_00187Not AvailableNegative201725 - 20295447461.1
tetraacyldisaccharide 4'-kinaseSAMEA3729771_00188Not AvailableNegative203009 - 20398935587.3
lipid a export atp-binding/permease msbaSAMEA3729771_00189Not AvailableNegative203986 - 20573464541.7
putative recombination protein with metallo-hydrolase domainSAMEA3729771_00190Not AvailableNegative205771 - 20803584104.8
integration host factor subunit betaSAMEA3729771_00191Not AvailableNegative208241 - 20852810736.8
30s ribosomal protein s1SAMEA3729771_00192Not AvailableNegative208680 - 21035361180.5

Displaying genes 291 – 300 of 5067 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total