Klebsiella pneumoniae strain EuSCAPE_TR189

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR189 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing a chemoheterotrophic energy source. This strain is characterized by its mobility, facilitated by the presence of flagella, and typically organizes itself in chains, pairs, or as single cells. Optimal growth occurs at 37°C, and it thrives within a mesophilic temperature range. The bacterium has a biotic relationship described as free-living, and it possesses a single replicon and a double membrane structure. EuSCAPE_TR189 is associated with a wide array of hosts, including Homo sapiens (humans), various avian species, and other metazoans, indicating its versatility and potential for zoonotic transmission. Klebsiella pneumoniae is known for its pathogenicity in humans, contributing to numerous health complications such as bacteremia, urinary tract infections, pneumonia, cystitis, and various intra-abdominal infections. It is also implicated in severe conditions like sepsis, neonatal sepsis, and liver abscesses. The broad spectrum of diseases associated with this strain underlines its clinical significance, particularly in immunocompromised individuals and those with existing health issues. The ecological role of Klebsiella pneumoniae strain EuSCAPE_TR189 highlights its adaptability in diverse environments and host organisms. This adaptability may facilitate its persistence in both clinical and natural settings, making it essential for ongoing surveillance in public health and infectious disease research.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR189

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR189
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR189 genome assembly,

Gene Summary

Adenine Count

1169731 bp

Thymine Count

1169975 bp

Guanine Count

1558220 bp

Cytosine Count

1562883 bp

Genome Length

5460809 bp

Protein-coding Genes

4991 genes

Non-Coding Genes

185 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
phosphate acetyltransferaseSAMEA3729757_03029Not AvailableNegative3215083 - 321723077229.7
acetate kinaseSAMEA3729757_03030Not AvailableNegative3217431 - 321863343276.9
membrane proteinSAMEA3729757_03031Not AvailablePositive3218971 - 321942617101.0
yfbuSAMEA3729757_03032Not AvailablePositive3219514 - 322000819400.2
putative phosphataseSAMEA3729757_03033Not AvailablePositive3220020 - 322067923510.2
transport proteinSAMEA3729757_03034Not AvailablePositive3220756 - 322258865845.9
nucleotidase yfbrSAMEA3729757_03035Not AvailableNegative3222633 - 322323222726.3
aspartate/tyrosine/aromatic aminotransferaseSAMEA3729757_03036Not AvailableNegative3223314 - 322453145485.9
lysr family transcriptional regulator lrhaSAMEA3729757_03037Not AvailablePositive3225404 - 322633033468.7
nadh-ubiquinone/plastoquinone oxidoreductase chain 3SAMEA3729757_03038Not AvailablePositive3227069 - 322742813334.2

Displaying genes 3131 – 3140 of 5176 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total