Klebsiella pneumoniae strain EuSCAPE_CZ016

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_CZ016 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. It can be found in various arrangements, including chains, pairs, and singles. This strain is classified as a chemoheterotroph and is capable of utilizing organic compounds as energy sources. As a facultative anaerobe, it can thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, situating it within the mesophilic temperature range. EuSCAPE_CZ016 is associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and various other metazoans and plants. This broad host range reflects its ecological versatility, indicating that it can adapt to diverse biological environments. It is notably free-living, which may contribute to its ability to establish infections in various hosts. In terms of health implications, K. pneumoniae strain EuSCAPE_CZ016 is pathogenic to humans and is linked to numerous clinical conditions such as bacteremia, urinary tract infections, pneumonia, and several types of sepsis, among others. Its capacity to cause serious health issues underscores the importance of understanding its biology and ecology, particularly in the context of antibiotic resistance and public health. The strain's ability to thrive in various hosts and environments may facilitate its transmission and persistence in both clinical and community settings, highlighting the need for continued surveillance and research on its pathogenic potential.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_CZ016

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_CZ016
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_CZ016 genome assembly,

Gene Summary

Adenine Count

1205609 bp

Thymine Count

1204942 bp

Guanine Count

1609687 bp

Cytosine Count

1602828 bp

Genome Length

5623066 bp

Protein-coding Genes

5097 genes

Non-Coding Genes

262 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
diguanylate cyclase/phosphodiesterase domain 2 (eal)SAMEA3729918_03021Not AvailablePositive3137816 - 313903345006.6
protein implicated in dna repair function with reca and mutsSAMEA3729918_03022Not AvailableNegative3139054 - 313956617848.8
small heat shock proteinSAMEA3729918_03023Not AvailableNegative3139731 - 314020417572.8
uncharacterised proteinSAMEA3729918_03024Not AvailablePositive3140702 - 31408063691.59
putative 2-component transcriptional regulatorSAMEA3729918_03025Not AvailablePositive3141216 - 314185123769.2
uncharacterised proteinSAMEA3729918_03026Not AvailableNegative3141848 - 31419704895.38
gifsy-2 prophage proteinSAMEA3729918_03027Not AvailablePositive3142325 - 314299925192.7
arac family transcriptional regulatorSAMEA3729918_03028Not AvailableNegative3143050 - 314389231082.7
uncharacterised proteinSAMEA3729918_03029Not AvailablePositive3143920 - 314430615110.1
dipeptidyl carboxypeptidase dcpSAMEA3729918_03030Not AvailableNegative3144384 - 314642977089.1

Displaying genes 3161 – 3170 of 5359 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total