Klebsiella pneumoniae strain EuSCAPE_CZ016

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_CZ016 is a Gram-negative, rod-shaped bacterium that exhibits mobility due to the presence of flagella. It can be found in various arrangements, including chains, pairs, and singles. This strain is classified as a chemoheterotroph and is capable of utilizing organic compounds as energy sources. As a facultative anaerobe, it can thrive in both aerobic and anaerobic environments, with an optimal growth temperature of 37°C, situating it within the mesophilic temperature range. EuSCAPE_CZ016 is associated with a wide range of hosts, including Homo sapiens, Gallus gallus, and various other metazoans and plants. This broad host range reflects its ecological versatility, indicating that it can adapt to diverse biological environments. It is notably free-living, which may contribute to its ability to establish infections in various hosts. In terms of health implications, K. pneumoniae strain EuSCAPE_CZ016 is pathogenic to humans and is linked to numerous clinical conditions such as bacteremia, urinary tract infections, pneumonia, and several types of sepsis, among others. Its capacity to cause serious health issues underscores the importance of understanding its biology and ecology, particularly in the context of antibiotic resistance and public health. The strain's ability to thrive in various hosts and environments may facilitate its transmission and persistence in both clinical and community settings, highlighting the need for continued surveillance and research on its pathogenic potential.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_CZ016

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_CZ016
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_CZ016 genome assembly,

Gene Summary

Adenine Count

1205609 bp

Thymine Count

1204942 bp

Guanine Count

1609687 bp

Cytosine Count

1602828 bp

Genome Length

5623066 bp

Protein-coding Genes

5097 genes

Non-Coding Genes

262 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hesa/moeb/thif family proteinSAMEA3729918_01420Not AvailablePositive1429882 - 143070328829.9
cysteine desulfuration protein csdeSAMEA3729918_01421Not AvailableNegative1430746 - 143117715674.8
cysteine sulfinate desulfinaseSAMEA3729918_01422Not AvailableNegative1431177 - 143238242575.8
lipoproteinSAMEA3729918_01423Not AvailablePositive1432574 - 14328048283.85
glycine cleavage system transcriptional activator gcvaSAMEA3729918_01424Not AvailablePositive1433249 - 143407330835.0
membrane proteinSAMEA3729918_01425Not AvailablePositive1434093 - 143448814385.0
rna 2'-o-ribose methyltransferase mtfaSAMEA3729918_01426Not AvailablePositive1434481 - 143558141905.4
l-fucose operon activatorSAMEA3729918_01427Not AvailableNegative1435630 - 143634026456.7
l-fucose mutarotaseSAMEA3729918_01428Not AvailableNegative1436399 - 143682115308.7
l-fuculokinaseSAMEA3729918_01429Not AvailableNegative1436823 - 143824151709.0

Displaying genes 1601 – 1610 of 5359 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total