Klebsiella pneumoniae strain EuSCAPE_PL047

Klebsiella pneumoniae strain EuSCAPE_PL047 is a Gram-negative, rod-shaped bacterium that exhibits a facultative anaerobic metabolism, utilizing chemoheterotrophic energy sources. This strain is characterized by its ability to exist in various cell arrangements, including chains, pairs, and singles, and it possesses flagella, indicating a degree of mobility. The optimal growth temperature for EuSCAPE_PL047 is 37°C, placing it within the mesophilic temperature range. This strain is of significant clinical importance due to its pathogenicity in humans. It is associated with numerous health effects, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. Notably, it can cause severe conditions such as sepsis and neonatal sepsis, as well as infections in other hosts, including Gallus gallus (chickens), Danio rerio (zebrafish), and various mammals. This broad host range highlights its adaptability and potential ecological impact. Klebsiella pneumoniae strain EuSCAPE_PL047 is nonsporulating and has a simple genomic structure with one replicon. It exists as a free-living organism, which may contribute to its transmission and persistence in various environments, particularly in human-associated habitats. Understanding the pathogenic mechanisms and ecological relationships of this strain is crucial for developing strategies to manage its clinical implications and prevent infections in both humans and other hosts.