Klebsiella pneumoniae strain EuSCAPE_TR302

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR302 is a significant Gram-negative bacterium categorized as a facultative anaerobe and a chemoheterotroph. This strain exhibits a rod-shaped morphology and can be found in various arrangements, including singles, pairs, and chains. It possesses flagella, indicating motility, and thrives optimally at 37°C, placing it within the mesophilic temperature range. This strain is notably associated with a wide range of hosts, primarily Homo sapiens, but also includes domestic animals and other metazoans such as Gallus gallus, Sus scrofa, and Danio rerio, among others. Klebsiella pneumoniae is recognized for its pathogenicity in humans, where it is implicated in multiple health concerns, including bacteremia, urinary tract infections, pneumonia, and various intra-abdominal infections. The broad spectrum of diseases associated with this strain highlights its clinical significance, particularly in severe conditions like sepsis and neonatal infections. In its ecological niche, Klebsiella pneumoniae strain EuSCAPE_TR302 exhibits a free-living biotic relationship while being host-associated. Its ability to inhabit diverse environments and infect multiple species underlines its adaptability and potential role in both health and disease across different biological systems. Understanding the pathogenic mechanisms and ecological roles of such strains is crucial for managing infections and developing targeted therapeutic strategies.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR302

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR302
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR302


Gene Summary

Adenine Count

1189542 bp

Thymine Count

1185552 bp

Guanine Count

1584210 bp

Cytosine Count

1582647 bp

Genome Length

5541951 bp

Protein-coding Genes

4861 genes

Non-Coding Genes

353 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
membrane proteinSAMEA3729896_00243Not AvailablePositive252864 - 25427951280.6
ribose abc transport system, periplasmic ribose-binding protein rbsbSAMEA3729896_00244Not AvailablePositive254411 - 25532532775.6
uncharacterised proteinSAMEA3729896_00245Not AvailablePositive255409 - 25573811597.6
gtp-binding and nucleic acid-binding protein ychfSAMEA3729896_00246Not AvailableNegative255821 - 25691239655.6
peptidyl-trna hydrolaseSAMEA3729896_00247Not AvailableNegative257030 - 25761421101.4
membrane proteinSAMEA3729896_00248Not AvailablePositive257887 - 25816210323.8
albicidin resistance proteinSAMEA3729896_00249Not AvailablePositive258384 - 25943039513.5
putative transporterSAMEA3729896_00250Not AvailableNegative259431 - 26108358178.2
ribose-phosphate pyrophosphokinaseSAMEA3729896_00251Not AvailableNegative261235 - 26218234296.6
4-diphosphocytidyl-2-c-methyl-d-erythritol kinaseSAMEA3729896_00252Not AvailableNegative262366 - 26321730676.8

Displaying genes 541 – 550 of 5214 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total