Klebsiella pneumoniae strain EuSCAPE_TR286

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR286 is a Gram-negative, rod-shaped bacterium that exhibits a range of pathogenic potential, primarily affecting Homo sapiens. It is characterized as a facultative anaerobe, able to thrive in various oxygen levels, and is classified as a chemoheterotroph, utilizing organic compounds as an energy source. This strain typically exists in chains, pairs, or as single cells, and possesses flagella, enabling mobility. The optimal growth temperature for EuSCAPE_TR286 is 37°C, placing it within the mesophilic range, which is conducive for growth in human hosts and other associated species. Notably, this strain is free-living but has various biotic relationships with a wide range of hosts, including domesticated animals like Gallus gallus (chickens), Sus scrofa (pigs), and Canis lupus familiaris (dogs), as well as other metazoans and plants. Klebsiella pneumoniae strain EuSCAPE_TR286 is linked to numerous health effects, including but not limited to bacteremia, urinary tract infections, pneumonia, and more serious conditions such as sepsis and meningitis. Its pathogenicity in humans underscores the importance of monitoring and controlling this strain, particularly in healthcare settings, where it can lead to severe infections. Considering its diverse host range and significant health implications, the ecological insight drawn from Klebsiella pneumoniae EuSCAPE_TR286 highlights the interplay between environmental factors and pathogenicity. This emphasizes the need for further research into its transmission dynamics and the potential impact of its presence in various ecological niches.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR286

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR286
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR286 genome assembly,

Gene Summary

Adenine Count

1198474 bp

Thymine Count

1205205 bp

Guanine Count

1593497 bp

Cytosine Count

1618306 bp

Genome Length

5615482 bp

Protein-coding Genes

5036 genes

Non-Coding Genes

300 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Hypothetical proteinSAMEA3729882_03307Not AvailableNegative3508322 - 350869013408.3
Hypothetical proteinSAMEA3729882_03308Not AvailableNegative3508693 - 350905513022.0
Gp12SAMEA3729882_03309Not AvailableNegative3509055 - 35092286615.85
Hypothetical proteinSAMEA3729882_03310Not AvailableNegative3509228 - 350960812910.5
Hypothetical proteinSAMEA3729882_03311Not AvailableNegative3509611 - 35098568519.99
Capsid proteinSAMEA3729882_03312Not AvailableNegative3509866 - 351096340536.4
Capsid proteinSAMEA3729882_03313Not AvailableNegative3510975 - 351140615105.9
Hypothetical proteinSAMEA3729882_03314Not AvailableNegative3511410 - 351279550637.4
Head morphogenesis proteinSAMEA3729882_03315Not AvailableNegative3513241 - 351423637230.0
Portal proteinSAMEA3729882_03316Not AvailableNegative3514199 - 351562052423.5

Displaying genes 81 – 90 of 5336 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total