Klebsiella pneumoniae strain EuSCAPE_TR178

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain EuSCAPE_TR178 is a Gram-negative, rod-shaped, facultative anaerobe that primarily serves as a chemoheterotroph. This strain is notable for its mobility, facilitated by the presence of flagella, and typically exhibits a cell arrangement in chains, pairs, or singles. EuSCAPE_TR178 thrives optimally at 37°C and falls within the mesophilic temperature range. This strain is free-living and associated with a variety of hosts, including Homo sapiens, Gallus gallus, and several other species across Metazoa, Viridiplantae, and more. Klebsiella pneumoniae is well-known for its pathogenic potential, particularly in humans, where it can cause a wide array of infections, including bacteremia, urinary tract infections, pneumonia, and more severe conditions such as sepsis and meningitis. The strain does not undergo sporulation and has a single replicon along with a double membrane structure, characteristic of its classification in the Enterobacteriaceae family. The ecological implications of Klebsiella pneumoniae strain EuSCAPE_TR178 highlight its adaptability and versatility in various environments and hosts. Its capacity to cause significant health issues underscores the importance of understanding its biology and pathogenic mechanisms to develop effective treatments and preventive measures against infections it may cause in humans and other species.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
Strainstrain EuSCAPE_TR178

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae strain EuSCAPE_TR178
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae strain EuSCAPE_TR178 genome assembly,

Gene Summary

Adenine Count

1140848 bp

Thymine Count

1133092 bp

Guanine Count

1520455 bp

Cytosine Count

1550953 bp

Genome Length

5345348 bp

Protein-coding Genes

4790 genes

Non-Coding Genes

215 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
aldo/keto reductaseSAMEA3729738_00280Not AvailableNegative283592 - 28444331840.0
arac family transcriptional regulatorSAMEA3729738_00281Not AvailablePositive284588 - 28551434738.8
uncharacterised proteinSAMEA3729738_00282Not AvailableNegative285763 - 28648225624.1
cytochrome c heme lyase subunit ccmhSAMEA3729738_00283Not AvailableNegative286865 - 28770730508.0
cytochrome c heme lyase subunit ccmlSAMEA3729738_00284Not AvailableNegative287704 - 28816216940.7
cytochrome c-type biogenesis protein ccmg/dsbe, thiol:disulfide oxidoreductaseSAMEA3729738_00285Not AvailableNegative288162 - 28871621035.5
cytochrome c heme lyase subunit ccmfSAMEA3729738_00286Not AvailableNegative288713 - 29066572390.1
cytochrome c-type biogenesis protein ccme, heme chaperoneSAMEA3729738_00287Not AvailableNegative290662 - 29112016767.2
cytochrome c-type biogenesis protein ccmd, interacts with ccmceSAMEA3729738_00288Not AvailableNegative291104 - 2913348408.06
cytochrome c-type biogenesis protein ccmc, putative heme lyase for ccmeSAMEA3729738_00289Not AvailableNegative291331 - 29206827458.4

Displaying genes 431 – 440 of 5005 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total